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How to get fromClarksdale to Chicagoby car, plane, taxi, bus, or train (Amtrak)

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There are 6 ways to get from Clarksdale to Chicago by car, plane, taxi, bus, or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Bill And Hillary Clinton National Airport, fly to Chicago O'Hare International Airport

    best
    1. Drive from Clarksdale to Bill And Hillary Clinton National Airport (LIT)car car
    2. Fly from Bill And Hillary Clinton National Airport (LIT) to Chicago O'Hare International Airport (ORD)plane plane LIT - ORD
    5h 37m
    $103–473

  2. Taxi, bus

    1. Take the taxi from Clarksdale to Batesville(Terza One Stop Shop)taxi taxi
    2. Take the bus from Batesville(Terza One Stop Shop) to Memphis Bus Stationbus bus
    3. Take the bus from Memphis Bus Station to Chicago Bus Stationbus bus
    12h 30m
    $212–322

  3. Train (Amtrak)

    1. Take the train from Marks Station to Chicago Union Stationtrain train City of New Orleans
    13h 4m
    $243–453

  4. Drive 605.1 mi

    1. Drive from Clarksdale to Chicagocar car 605.1 mi
    9h 59m
    $111–160

  5. Taxi, bus to Memphis, fly to Chicago Midway International Airport

    1. Take the taxi from Clarksdale to Batesville(Terza One Stop Shop)taxi taxi
    2. Take the bus from Batesville(Terza One Stop Shop) to Memphis Bus Stationbus bus
    3. Fly from Memphis (MEM) to Chicago Midway International Airport (MDW)plane plane MEM - MDW
    6h 14m
    $210–598

  6. Taxi, bus to Memphis, fly to Chicago O'Hare International Airport

    1. Take the taxi from Clarksdale to Batesville(Terza One Stop Shop)taxi taxi
    2. Take the bus from Batesville(Terza One Stop Shop) to Memphis Bus Stationbus bus
    3. Fly from Memphis (MEM) to Chicago O'Hare International Airport (ORD)plane plane MEM - ORD
    6h 45m
    $200–538

Bill And Hillary Clinton National Airport (LIT) to Chicago O'Hare International Airport (ORD) flights

Calendar62Weekly Planes
Duration2h 27mAverage Duration
Ticket$77Cheapest Price
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Questions & Answers

Map of how to get from Clarksdale to Chicago.ExpandLaunch map view
  • Distance: 712.6 mi
  • Duration: 5h 37m

What companies run services between Clarksdale, MS, USA and Chicago, IL, USA?

Amtrak operates a train from Marks Station to Chicago Union Station once daily. Tickets cost $190–390 and the journey takes 12h 40m.

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