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How to get fromCleveland Airport (CLE) to La Crosseby plane, train (Amtrak), bus (Greyhound, Flixbus), car, or bus

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There are 6 ways to get from Cleveland Airport (CLE) to La Crosse by plane, train (Amtrak), bus (Greyhound, Flixbus), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to La Crosse

    best
    1. Fly from Cleveland-Hopkins International Airport (CLE) to La Crosse (LSE)plane plane CLE - LSE
    4h 16m
    $101–470

  2. Train (Amtrak)

    1. Take the train from Cleveland Amtrak to Chicago Union Stationtrain train Floridian / ...
    2. Take the train from Chicago Union Station to La Crosse Amtrak Stationtrain train Empire Builder / ...
    14h 35m
    $188–422

  3. Bus via Chicago

    1. Take the bus from Cleveland Bus Station to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus
    3. Take the bus from Milwaukee to La Crossebus bus
    15h 50m
    $116–204

  4. Drive 615.1 mi

    1. Drive from Cleveland Airport (CLE) to La Crossecar car 615.1 mi
    10h 12m
    $113–163

  5. Fly to Rochester, bus

    1. Fly from Cleveland-Hopkins International Airport (CLE) to Rochester (RST)plane plane CLE - RST
    2. Take the bus from Rochester to La Crossebus bus
    7h 49m
    $115–541

  6. Bus

    1. Take the bus from Cleveland Bus Station to Detroit Bus Stationbus bus
    2. Take the bus from Detroit Bus Station to Appleton Transit Centerbus bus
    3. Take the bus from Appleton Valley Transit to La Crosse Grand River Stationbus bus
    20h 50m
    $136–222

Cleveland Airport (CLE) to La Crosse by subway, foot, and bus

Calendar7Weekly Services
Duration15h 50mAverage Duration
Ticket$116Cheapest Price
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Questions & Answers

Map of how to get from Cleveland Airport (CLE) to La Crosse.ExpandLaunch map view
  • Distance: 515.7 mi
  • Duration: 4h 16m

What companies run services between Cleveland Airport (CLE), USA and La Crosse, WI, USA?

United Airlines and American Airlines fly from Cleveland-Hopkins International Airport (CLE) to La Crosse (LSE) every 4 hours. Alternatively, you can take a subway from Airport Station to La Crosse Amtrak Station via Tower City Station Track 13, Cleveland Amtrak, and Chicago Union Station in around 14h 35m.

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