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How to get fromCleveland Clinic to Columbusby bus, car, plane, or bus (Greyhound)

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There are 6 ways to get from Cleveland Clinic to Columbus by bus, car, plane, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Cleveland Ohio Greyhound Station to Columbus - Downtown - Mound Stbus bus Cleveland
    3h 44m
    $16–52

  2. Bus via Akron

    cheapest
    1. Take the bus from Euclid Ave & E. 100th St @ Cleveland Cl to Robert K Pfaff Transit Center - Akronbus bus 61
    2. Take the bus from Robert K Pfaff Transit Center - Akron to Columbus - 306 E Mount Stbus bus Route D
    6h 17m
    $14–19

  3. Drive 144.1 mi

    1. Drive from Cleveland Clinic to Columbuscar car 144.1 mi
    2h 27m
    $27–38

  4. Fly

    1. Fly from Cleveland-Hopkins International Airport (CLE) to John Glenn Columbus International Airport (CMH)plane plane CLE - CMH
    6h 7m
    $854–956

  5. Bus via Brookpark Station (Greyhound)

    1. Take the bus from Cleveland Bus Station to Columbusbus bus Greyhound US0105
    4h 33m
    $22–42

  6. Bus via Columbus, Ohio Greyhound Station

    1. Take the bus from Cleveland Ohio Greyhound Station to Columbus, Ohio Greyhound Stationbus bus 379 D
    6h 36m
    $62–82

Cleveland Clinic to Columbus by foot and bus

Calendar14Weekly Services
Duration3h 44mAverage Duration
Ticket$16Cheapest Price
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Questions & Answers

Map of how to get from Cleveland Clinic to Columbus.ExpandLaunch map view
  • Distance: 147.6 mi
  • Duration: 3h 44m

What companies run services between Cleveland Clinic, OH, USA and Columbus, OH, USA?

Barons Bus operates a bus from Cleveland Ohio Greyhound Station to Columbus - Downtown - Mound St twice daily. Tickets cost $13–50 and the journey takes 2h 15m. Alternatively, Delta, Southwest Airlines, and two other airlines fly from Cleveland-Hopkins International Airport (CLE) to John Glenn Columbus International Airport (CMH) every 2 hours.

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