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How to get fromCleveland Clinic to South Carolinaby plane, taxi, train (Amtrak), car, or bus

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There are 5 ways to get from Cleveland Clinic to South Carolina by plane, taxi, train (Amtrak), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Cleveland-Hopkins International Airport to Charlotte Douglas International Airport, taxi

    best
    1. Fly from Cleveland-Hopkins International Airport (CLE) to Charlotte Douglas International Airport (CLT)plane plane CLE - CLT
    2. Take the taxi from Charlotte-Airport-CLT to Rock Hilltaxi taxi
    4h 18m
    $182–752

  2. Bus to Akron, fly to Charleston International Airport

    cheapest
    1. Take the bus from Euclid Ave & E. 100th St @ Cleveland Cl to Robert K Pfaff Transit Center - Akronbus bus
    2. Fly from Akron (CAK) to Charleston International Airport (CHS)plane plane CAK - CHS
    6h 41m
    $113–253

  3. Train (Amtrak)

    1. Take the train from Cleveland Amtrak to Petersburg Amtrak Stationtrain train Floridian
    2. Take the train from Petersburg Amtrak Station to Charleston Amtrak Stationtrain train Silver Meteor / ...
    24h 19m
    $322–662

  4. Drive 712.6 mi

    1. Drive from Cleveland Clinic to Charlestoncar car 712.6 mi
    12h 16m
    $130–188

  5. Bus to Akron, fly to Charlotte Douglas International Airport, taxi

    1. Take the bus from Euclid Ave & E. 100th St @ Cleveland Cl to Robert K Pfaff Transit Center - Akronbus bus
    2. Fly from Akron (CAK) to Charlotte Douglas International Airport (CLT)plane plane CAK - CLT
    3. Take the taxi from Charlotte-Airport-CLT to Rock Hilltaxi taxi
    6h 9m
    $161–591

Cleveland-Hopkins International Airport (CLE) to Charlotte Douglas International Airport (CLT) flights

Calendar74Weekly Planes
Duration3h 12mAverage Duration
Ticket$109Cheapest Price
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Questions & Answers

Map of how to get from Cleveland Clinic to South Carolina.ExpandLaunch map view
  • Distance: 476.1 mi
  • Duration: 4h 18m

What companies run services between Cleveland Clinic, OH, USA and South Carolina, USA?

You can take a vehicle from Cleveland Clinic to Charleston via E 105Th St-Quincy Av Station, Tower City Station Track 8, Cleveland Amtrak, Petersburg Amtrak Station, and Charleston Amtrak Station in around 24h 19m.

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