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How to get fromCleveland to Charlestonby plane, train (Amtrak), bus (Greyhound), car, bus, or train

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There are 6 ways to get from Cleveland to Charleston by plane, train (Amtrak), bus (Greyhound), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Cleveland-Hopkins International Airport

    best
    1. Fly from Cleveland-Hopkins International Airport (CLE) to Charleston International Airport (CHS)plane plane CLE - CHS
    6h 51m
    $100–504

  2. Train (Amtrak)

    1. Take the train from Cleveland Amtrak to Petersburg Amtrak Stationtrain train Floridian
    2. Take the train from Petersburg Amtrak Station to Charleston Amtrak Stationtrain train Silver Meteor / ...
    22h 25m
    $324–649

  3. Bus

    1. Take the bus from Cleveland Bus Station to Atlanta Bus Stationbus bus Greyhound US0105
    2. Take the bus from Atlanta Bus Station to Charleston Bus Stationbus bus Greyhound US0641S
    34h 19m
    $251–388

  4. Drive 711.5 mi

    1. Drive from Cleveland to Charlestoncar car 711.5 mi
    12h 13m
    $130–188

  5. Bus to Akron, fly

    1. Take the bus from Cleveland, OH to Robert K Pfaff Transit Center - Akronbus bus
    2. Fly from Akron (CAK) to Charleston International Airport (CHS)plane plane CAK - CHS
    6h 30m
    $115–286

  6. Train to Pittsburgh International Airport, fly

    1. Take the train from Cleveland Amtrak to Pittsburgh Amtrak Stationtrain train
    2. Fly from Pittsburgh International Airport (PIT) to Charleston International Airport (CHS)plane plane PIT - CHS
    9h 5m
    $127–532

Cleveland to Charleston by bus

Calendar7Weekly Buses
Duration34h 19mAverage Duration
Ticket$251Cheapest Price
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Questions & Answers

Map of how to get from Cleveland to Charleston.ExpandLaunch map view
  • Distance: 623 mi
  • Duration: 6h 51m

What companies run services between Cleveland, OH, USA and Charleston, SC, USA?

Southwest Airlines, Delta, and two other airlines fly from Cleveland-Hopkins International Airport (CLE) to Charleston International Airport (CHS) hourly. Alternatively, you can take a train from Cleveland Amtrak to Charleston via Petersburg Amtrak Station and Charleston Amtrak Station in around 22h 25m.

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