There are 5 ways to get from Cleveland to East Saint Louis by plane, bus (Greyhound), train (Amtrak), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Cleveland-Hopkins International Airport (CLE) to Lambert–St. Louis International Airport (STL)plane CLE - STL
4h 8m$106–656Bus via Indianapolis
cheapest- Take the bus from Cleveland to Toledobus
- Take the bus from Toledo to Indianapolisbus
- Take the bus from Indianapolis Union Station to St Louis Bus Stationbus
12h 1m$75–178Train (Amtrak)
- Take the train from Cleveland Amtrak to Chicago Union Stationtrain Floridian / ...
- Take the train from Chicago Union Station to St. Louistrain Lincoln Service / ...
12h 48m$340–530Drive 550.7 mi
- Drive from Cleveland to East Saint Louiscar 550.7 mi
9h 19m$101–146Bus
- Take the bus from Cleveland Ohio Greyhound Station to Columbus, Ohio Greyhound Stationbus 379 D
- Take the bus from Columbus to St Louis Bus Stationbus Greyhound US0421
16h 7m$140–340
Cleveland to East Saint Louis by bus and train
Comparing Your Travel Options
The cheapest way to get from Cleveland to East Saint Louis is to bus via Indianapolis which costs $75 - $180 and takes 12h 1m.
The fastest way to get from Cleveland to East Saint Louis is to fly which takes 4h 8m and costs $100 - $700.
No, there is no direct bus from Cleveland to East Saint Louis station. However, there are services departing from Cleveland and arriving at St Louis Bus Station via Toledo and Indianapolis Union Station. The journey, including transfers, takes approximately 12h 1m.
No, there is no direct train from Cleveland to East Saint Louis station. However, there are services departing from Cleveland Amtrak and arriving at 5TH & MISSOURI station via Chicago Union Station and CIVIC CENTER station. The journey, including transfers, takes approximately 12h 48m.
The distance between Cleveland and East Saint Louis is 520 miles. The road distance is 553.9 miles.
The best way to get from Cleveland to East Saint Louis without a car is to bus via Indianapolis which takes 12h 1m and costs $75 - $180.
It takes approximately 4h 8m to get from Cleveland to East Saint Louis, including transfers.
Cleveland to East Saint Louis bus services, operated by Barons Bus, depart from Cleveland station.
Cleveland to East Saint Louis train services, operated by Amtrak, depart from Cleveland Amtrak station.
The best way to get from Cleveland to East Saint Louis is to fly which takes 4h 8m and costs $100 - $700. Alternatively, you can bus via Indianapolis, which costs $75 - $180 and takes 12h 1m, you could also train, which costs $340 - $550 and takes 12h 48m.
What companies run services between Cleveland, OH, USA and East Saint Louis, IL, USA?
Southwest Airlines, United Airlines, and Delta fly from Cleveland-Hopkins International Airport (CLE) to Lambert–St. Louis International Airport (STL) every 4 hours. Alternatively, you can take a bus from Cleveland to 5TH & MISSOURI station via Toledo, Indianapolis Union Station, St Louis Bus Station, and CIVIC CENTER station in around 12h 1m.
- Website
- southwest.com
Flights from Cleveland-Hopkins International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- $100–650
Flights from Cleveland-Hopkins International Airport to Lambert–St. Louis International Airport via Nashville
- Ave. Duration
- 4h
- When
- Monday, Thursday, Friday, Sunday, and Tuesday
- Estimated price
- $120–700
Flights from Cleveland-Hopkins International Airport to Lambert–St. Louis International Airport via Chicago Midway
- Ave. Duration
- 4h 5m
- When
- Saturday
- Estimated price
- $110–650
- Website
- united.com
Flights from Cleveland-Hopkins International Airport to Lambert–St. Louis International Airport via Chicago O'Hare
- Ave. Duration
- 4h 19m
- When
- Every day
- Estimated price
- $110–650
- Website
- delta.com
Flights from Cleveland-Hopkins International Airport to Lambert–St. Louis International Airport via Detroit
- Ave. Duration
- 4h 21m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $100–650
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Cleveland Amtrak to Chicago Union Station
- Ave. Duration
- 6h 46m
- Frequency
- 3 times a day
- Estimated price
- $180–290
- Website
- Amtrak
Train from Chicago Union Station to St. Louis
- Ave. Duration
- 4h 46m
- Frequency
- 5 times a day
- Estimated price
- $150–240
- Website
- Amtrak
- Phone
- +1 888-378-3823
- [email protected]
- Website
- Barons Bus
Bus from Cleveland to Toledo
- Ave. Duration
- 1h 45m
- Frequency
- Once daily
- Estimated price
- $11–45
- Website
- Barons Bus
Bus from Toledo to Indianapolis
- Ave. Duration
- 4h 5m
- Frequency
- Once daily
- Estimated price
- $21–65
- Website
- Barons Bus
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Indianapolis Union Station to St Louis Bus Station
- Ave. Duration
- 3h 55m
- Frequency
- 3 times a day
- Estimated price
- $40–65
- Website
- Greyhound
Bus from Columbus to St Louis Bus Station
- Ave. Duration
- 9h 25m
- Frequency
- 3 times a day
- Estimated price
- $75–120
- Website
- Greyhound
- Phone
- +1 502-368-5644 x 135
- Website
- Miller Transportation
Bus from Cleveland Ohio Greyhound Station to Columbus, Ohio Greyhound Station
- Ave. Duration
- 5h 10m
- Frequency
- Once daily
- Estimated price
- $60–220
- Website
- Miller Transportation
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Booking & Getting There
Cleveland to East Saint Louis bus services, operated by Barons Bus, arrive at Toledo station.
East Saint Louis is 1h behind Cleveland. It is currently 9:02 PM in Cleveland and 8:02 PM in East Saint Louis.
Cleveland to East Saint Louis train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Cleveland to East Saint Louis is 554 miles. It takes approximately 9h 19m to drive from Cleveland to East Saint Louis.
There are 542+ hotels available in East Saint Louis.












