Rome2Rio

How to get fromCleveland to Florenceby plane, bus (Greyhound), train (Amtrak), car, train, or bus

Find Transport to Florence

See all options

There are 5 ways to get from Cleveland to Florence by plane, bus (Greyhound), train (Amtrak), car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Cleveland-Hopkins International Airport (CLE) to Florence Regional Airport (FLO)plane plane CLE - FLO
    5h 25m
    $88–466

  2. Bus

    cheapest
    1. Take the bus from Cleveland, OH to Charleston, WVbus bus
    2. Take the bus from Charleston, WV to Charlotte Bus Stationbus bus
    3. Take the bus from Charlotte Bus Station to Camdenbus bus
    4. Take the bus from Camden to Florence Bus Stationbus bus
    16h 15m
    $84–168

  3. Train (Amtrak)

    1. Take the train from Cleveland Amtrak to Petersburg Amtrak Stationtrain train Floridian
    2. Take the train from Petersburg Amtrak Station to Florence Stationtrain train Palmetto / ...
    20h 55m
    $220–487

  4. Drive  608.3 mi

    1. Drive from Cleveland to Florencecar car 608.3 mi
    11h
    $111–161

  5. Train, bus

    1. Take the train from Cleveland Amtrak to Raleigh Union Stationtrain train Floridian
    2. Take the bus from Raleigh Bus Station to Florence Bus Stationbus bus Greyhound US0642S / ...
    22h 24m
    $220–465

Cleveland to Florence by bus

Calendar7Weekly Buses
Duration16h 15mAverage Duration
Ticket$84Cheapest Price
See schedules

Questions & Answers

Map of how to get from Cleveland to Florence.ExpandLaunch map view
  • Distance: 525.4 mi
  • Duration: 5h 25m

What companies run services between Cleveland, OH, USA and Florence, SC, USA?

American Airlines flies from Cleveland-Hopkins International Airport (CLE) to Florence Regional Airport (FLO) 4 times a day. Alternatively, you can take a bus from Cleveland, OH to Florence Bus Station via Charleston, WV, Charlotte Bus Station, and Camden in around 16h 15m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers