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How to get fromCleveland to Florence Stationby plane, bus (Greyhound), train (Amtrak), or car

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There are 4 ways to get from Cleveland to Florence Station by plane, bus (Greyhound), train (Amtrak), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Cleveland-Hopkins International Airport (CLE) to Florence Regional Airport (FLO)plane plane CLE - FLO
    5h 51m
    $92–464
  2. Bus

    cheapest
    1. Take the bus from Cleveland, OH to Charleston, WVbus bus
    2. Take the bus from Charleston, WV to Charlotte Bus Stationbus bus
    3. Take the bus from Charlotte Bus Station to Camdenbus bus
    4. Take the bus from Camden to Florence Bus Stationbus bus
    16h 39m
    $84–184
  3. Train (Amtrak)

    1. Take the train from Cleveland Amtrak to Petersburg Amtrak Stationtrain train Floridian
    2. Take the train from Petersburg Amtrak Station to Florence Stationtrain train Palmetto / ...
    20h 55m
    $269–554
  4. Drive 608.7 mi

    1. Drive from Cleveland to Florence Stationcar car 608.7 mi
    11h 4m
    $112–161

Cleveland to Florence Station by train (Amtrak)

Calendar7Weekly Trains
Duration20h 55mAverage Duration
Ticket$269Cheapest Price
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Questions & Answers

What companies run services between Cleveland, OH, USA and Florence Station, SC, USA?

American Airlines flies from Cleveland-Hopkins International Airport (CLE) to Florence Regional Airport (FLO) every 4 hours. Alternatively, you can take a bus from Cleveland, OH to Florence Station via Charleston, WV, Charlotte Bus Station, Camden, and Florence Bus Station in around 16h 39m.

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