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How to get fromCleveland to Greenvilleby plane, bus (Greyhound), train, bus, car, or taxi

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There are 6 ways to get from Cleveland to Greenville by plane, bus (Greyhound), train, bus, car, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Greenville–Spartanburg International Airport

    best
    1. Fly from Cleveland-Hopkins International Airport (CLE) to Greenville–Spartanburg International Airport (GSP)plane plane CLE - GSP
    5h 18m
    $148–698

  2. Drive 582.7 mi

    cheapest
    1. Drive from Cleveland to Greenvillecar car 582.7 mi
    10h 30m
    $107–154

  3. Bus via Charleston

    1. Take the bus from Cleveland, OH to Charleston, WVbus bus
    2. Take the bus from Charleston, WV to Charlotte Bus Stationbus bus
    3. Take the bus from Charlotte to Taqueria Guadalajara - Greenvillebus bus
    15h 59m
    $122–311

  4. Train, bus

    1. Take the train from Cleveland Amtrak to Carytrain train
    2. Take the train from Cary to Charlotte Amtrak Stationtrain train
    3. Take the bus from Charlotte to Taqueria Guadalajara - Greenvillebus bus
    26h 14m
    $347–759

  5. Fly to Asheville Regional Airport, taxi

    1. Fly from Cleveland-Hopkins International Airport (CLE) to Asheville Regional Airport (AVL)plane plane CLE - AVL
    2. Take the taxi from Asheville-Airport-AVL to Greenvilletaxi taxi
    5h 59m
    $222–622

  6. Bus

    1. Take the bus from Cleveland Bus Station to Atlanta Bus Stationbus bus Greyhound US0105
    2. Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus bus Charlotte
    27h 16m
    $186–404

Cleveland-Hopkins International Airport (CLE) to Greenville–Spartanburg International Airport (GSP) flights

Calendar109Weekly Planes
Duration4h 9mAverage Duration
Ticket$118Cheapest Price
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Questions & Answers

Map of how to get from Cleveland to Greenville.ExpandLaunch map view
  • Distance: 474.6 mi
  • Duration: 5h 18m

What companies run services between Cleveland, OH, USA and Greenville, SC, USA?

Delta, Southwest Airlines, and two other airlines fly from Cleveland-Hopkins International Airport (CLE) to Greenville–Spartanburg International Airport (GSP) hourly. Alternatively, you can take a bus from Cleveland, OH to Greenville via Charleston, WV, Charlotte Bus Station, Trade St & Graham St, Transit Center- Bay A, Transit Center- Bay O, Tryon St & Dorton St, Charlotte, and Taqueria Guadalajara - Greenville in around 15h 59m.

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