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How to get fromCleveland to Hartsvilleby plane, taxi, bus, train, or car

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There are 6 ways to get from Cleveland to Hartsville by plane, taxi, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Cleveland-Hopkins International Airport to Florence Regional Airport, taxi

    best
    1. Fly from Cleveland-Hopkins International Airport (CLE) to Florence Regional Airport (FLO)plane plane CLE - FLO
    2. Take the taxi from Florence Regional Airport (FLO) to Hartsvilletaxi taxi
    5h 55m
    $158–562

  2. Bus to Akron, fly to Myrtle Beach, drive

    cheapest
    1. Take the bus from Cleveland to Akronbus bus
    2. Fly from Akron (CAK) to Myrtle Beach (MYR)plane plane CAK - MYR
    3. Drive from Myrtle Beach (MYR) to Hartsvillecar car
    6h 55m
    $69–358

  3. Bus, taxi

    1. Take the bus from Cleveland, OH to Charleston, WVbus bus
    2. Take the bus from Charleston, WV to Charlotte Bus Stationbus bus
    3. Take the bus from Charlotte Bus Station to Camdenbus bus
    4. Take the taxi from Camden to Hartsvilletaxi taxi
    15h 2m
    $197–306

  4. Train, taxi (Amtrak)

    1. Take the train from Cleveland Amtrak to Camden Stationtrain train Floridian
    2. Take the taxi from Camden Station to Hartsvilletaxi taxi
    22h 37m
    $345–675

  5. Drive  586.2 mi

    1. Drive from Cleveland to Hartsvillecar car 586.2 mi
    10h 29m
    $107–155

  6. Fly Cleveland-Hopkins International Airport to Charlotte Douglas International Airport, bus, taxi

    1. Fly from Cleveland-Hopkins International Airport (CLE) to Charlotte Douglas International Airport (CLT)plane plane CLE - CLT
    2. Take the bus from Charlotte Bus Station to Camdenbus bus
    3. Take the taxi from Camden to Hartsvilletaxi taxi
    7h 8m
    $238–828

Cleveland-Hopkins International Airport (CLE) to Florence Regional Airport (FLO) flights

Calendar42Weekly Planes
Duration6h 27mAverage Duration
Ticket$78Cheapest Price
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Comparing Your Travel Options

Map of how to get from Cleveland to Hartsville.ExpandLaunch map view
  • Distance: 548.8 mi
  • Duration: 5h 55m

What companies run services between Cleveland, OH, USA and Hartsville, SC, USA?

There is no direct connection from Cleveland to Hartsville. However, you can take the subway to Airport Station, walk to Cleveland-Hopkins International Airport (CLE) airport, fly to Florence Regional Airport (FLO), then take the taxi to Hartsville. Alternatively, you can take the bus to Charleston, WV, take the bus to Charlotte Bus Station, take the bus to Camden, then take the taxi to Hartsville.

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