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How to get fromCleveland to Jeffersonvilleby bus (Amtrak), train, bus, car, plane, or bus (Greyhound, Amtrak)

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There are 7 ways to get from Cleveland to Jeffersonville by bus (Amtrak), train, bus, car, plane, or bus (Greyhound, Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Cleveland to Toledobus bus
    2. Take the bus from Toledo to Indianapolisbus bus
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    11h 5m
    $55–158

  2. Train, bus via Chicago (Amtrak)

    1. Take the train from Cleveland Amtrak to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Indianapolistrain train
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    16h 27m
    $311–506

  3. Drive  347 mi

    1. Drive from Cleveland to Jeffersonvillecar car 347 mi
    5h 51m
    $64–92

  4. Fly

    1. Fly from Cleveland-Hopkins International Airport (CLE) to Louisville International Airport (SDF)plane plane CLE - SDF
    7h 16m
    $114–758

  5. Train, bus

    1. Take the train from Cleveland Amtrak to Toledotrain train
    2. Take the bus from Toledo to Indianapolisbus bus
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    11h 29m
    $103–204

  6. Train, bus #2

    1. Take the train from Cleveland Amtrak to Toledotrain train
    2. Take the bus from Toledo Bus Stop to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    11h 44m
    $117–199

  7. Bus via Columbus

    1. Take the bus from Cleveland Ohio Greyhound Station to Columbus, Ohio Greyhound Stationbus bus
    2. Take the bus from Columbus to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    14h 24m
    $115–315

Cleveland to Jeffersonville by bus and foot

Calendar7Weekly Services
Duration11h 5mAverage Duration
Ticket$55Cheapest Price
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Comparing Your Travel Options

Map of how to get from Cleveland to Jeffersonville.ExpandLaunch map view
  • Distance: 453.4 mi
  • Duration: 11h 5m

What companies run services between Cleveland, OH, USA and Jeffersonville, IN, USA?

You can take a bus from Cleveland to Court @ Meigs via Toledo, Indianapolis Union Station, Louisville, KY, and Liberty @ Roy Wilkins in around 11h 5m. Alternatively, Delta, Southwest Airlines, and two other airlines fly from Cleveland-Hopkins International Airport (CLE) to Louisville International Airport (SDF) hourly.

Airlines
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Need to know: Greyhound

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