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How to get fromCleveland to Kirksvilleby plane, train (Amtrak), bus, train, car, or shuttle

Find Transport to Kirksville

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There are 9 ways to get from Cleveland to Kirksville by plane, train (Amtrak), bus, train, car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Cleveland-Hopkins International Airport to Kirksville Regional Airport

    best
    1. Fly from Cleveland-Hopkins International Airport (CLE) to Kirksville Regional Airport (IRK)plane plane CLE - IRK
    6h 19m
    $128–528

  2. Fly Cleveland-Hopkins International Airport to Burlington Municipal Airport, drive

    cheapest
    1. Fly from Cleveland-Hopkins International Airport (CLE) to Burlington Municipal Airport (BRL)plane plane CLE - BRL
    2. Drive from Burlington Municipal Airport (BRL) to Kirksvillecar car
    8h 10m
    $68–308

  3. Train (Amtrak)

    1. Take the train from Cleveland Amtrak to Chicago Union Stationtrain train Floridian / ...
    2. Take the train from Chicago Union Station to La Plata Stationtrain train Southwest Chief
    12h 55m
    $251–476

  4. Bus, train

    1. Take the bus from Cleveland to Toledobus bus
    2. Take the bus from Toledo to Indianapolis, INbus bus
    3. Take the bus from Indianapolis Union Station to Galesburgbus bus
    4. Take the train from Galesburg Amtrak Station to La Plata Stationtrain train
    16h 15m
    $157–355

  5. Drive 661.9 mi

    1. Drive from Cleveland to Kirksvillecar car 661.9 mi
    12h 29m
    $121–175

  6. Fly Cleveland-Hopkins International Airport to Lambert–St. Louis International Airport, bus, shuttle

    1. Fly from Cleveland-Hopkins International Airport (CLE) to Lambert–St. Louis International Airport (STL)plane plane CLE - STL
    2. Take the bus from Saint Louis to Bowling Greenbus bus
    3. Take a shuttle bus from Bowling Green, Mo to Columbiashuttle bus
    4. Take a shuttle bus from Columbia to Hy-Vee - Kirksvilleshuttle bus
    10h 2m
    $528–954

  7. Bus to Akron, fly to Kirksville Regional Airport

    1. Take the bus from Cleveland, OH to Robert K Pfaff Transit Center - Akronbus bus
    2. Fly from Akron (CAK) to Kirksville Regional Airport (IRK)plane plane CAK - IRK
    11h 47m
    $108–459

  8. Fly Cleveland-Hopkins International Airport to Chicago Midway International Airport, train

    1. Fly from Cleveland-Hopkins International Airport (CLE) to Chicago Midway International Airport (MDW)plane plane CLE - MDW
    2. Take the train from Chicago Union Station to La Plata Stationtrain train
    9h 43m
    $208–636

  9. Train, bus (Amtrak)

    1. Take the train from Cleveland Amtrak to Toledotrain train
    2. Take the bus from Toledo to Chicago Union Stationbus bus
    3. Take the train from Chicago Union Station to La Plata Stationtrain train
    13h 40m
    $260–445

Cleveland-Hopkins International Airport (CLE) to Kirksville Regional Airport (IRK) flights

Calendar20Weekly Planes
Duration6h 12mAverage Duration
Ticket$91Cheapest Price
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Questions & Answers

Map of how to get from Cleveland to Kirksville.ExpandLaunch map view
  • Distance: 586.7 mi
  • Duration: 6h 19m

What companies run services between Cleveland, OH, USA and Kirksville, MO, USA?

American Airlines, Corporate Flight Management Inc, and two other airlines fly from Cleveland-Hopkins International Airport (CLE) to Kirksville Regional Airport (IRK) 3 times a day. Alternatively, you can take a train from Cleveland Amtrak to Kirksville via Chicago Union Station and La Plata Station in around 12h 55m.

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