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How to get fromCleveland to La Crosseby plane, train (Amtrak), bus (Greyhound, Flixbus), car, bus, train, or bus (Greyhound)

Find Transport to La Crosse

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There are 7 ways to get from Cleveland to La Crosse by plane, train (Amtrak), bus (Greyhound, Flixbus), car, bus, train, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Cleveland-Hopkins International Airport to La Crosse

    best
    1. Fly from Cleveland-Hopkins International Airport (CLE) to La Crosse (LSE)plane plane CLE - LSE
    5h 42m
    $102–496

  2. Bus to Akron, fly to La Crosse

    cheapest
    1. Take the bus from Cleveland to Akronbus bus
    2. Fly from Akron (CAK) to La Crosse (LSE)plane plane CAK - LSE
    8h 48m
    $87–427

  3. Train (Amtrak)

    1. Take the train from Cleveland Amtrak to Chicago Union Stationtrain train Floridian / ...
    2. Take the train from Chicago Union Station to La Crosse Amtrak Stationtrain train Empire Builder / ...
    12h 45m
    $336–526

  4. Bus via Milwaukee

    1. Take the bus from Cleveland to Chicagobus bus
    2. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus
    3. Take the bus from Milwaukee to La Crossebus bus
    14h 49m
    $101–182

  5. Drive  623.6 mi

    1. Drive from Cleveland to La Crossecar car 623.6 mi
    10h 23m
    $107–154

  6. Fly Cleveland-Hopkins International Airport to Minneapolis–Saint Paul International Airport, train

    1. Fly from Cleveland-Hopkins International Airport (CLE) to Minneapolis–Saint Paul International Airport (MSP)plane plane CLE - MSP
    2. Take the train from St. Paul-Minneapolis to La Crosse Amtrak Stationtrain train
    8h 1m
    $874–1,116

  7. Bus

    1. Take the bus from Cleveland Bus Station to Chicago Bus Stationbus bus
    2. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    3. Take the bus from Madison to La Crossebus bus
    16h 41m
    $122–208

Cleveland to La Crosse by train (Amtrak)

Calendar21Weekly Trains
Duration12h 45mAverage Duration
Ticket$336Cheapest Price
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Comparing Your Travel Options

Map of how to get from Cleveland to La Crosse.ExpandLaunch map view
  • Distance: 527 mi
  • Duration: 5h 42m

What companies run services between Cleveland, OH, USA and La Crosse, WI, USA?

American Airlines and United Airlines fly from Cleveland-Hopkins International Airport (CLE) to La Crosse (LSE) 4 times a day. Alternatively, you can take a train from Cleveland Amtrak to La Crosse Amtrak Station via Chicago Union Station in around 12h 45m.

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