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How to get fromCleveland to Louisville, KYby bus, car, plane, or bus (Greyhound)

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There are 5 ways to get from Cleveland to Louisville, KY by bus, car, plane, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Cleveland Ohio Greyhound Station to Louisville, KY Bus Stationbus bus Cleveland
    6h 50m
    $35–120

  2. Drive 348.1 mi

    1. Drive from Cleveland to Louisville, KYcar car 348.1 mi
    5h 52m
    $64–92

  3. Fly to Louisville International Airport

    1. Fly from Cleveland-Hopkins International Airport (CLE) to Louisville International Airport (SDF)plane plane CLE - SDF
    6h 30m
    $104–606

  4. Bus via Brookpark Station (Greyhound)

    1. Take the bus from Cleveland Bus Station to Louisville Bus Stationbus bus Greyhound US0105
    10h 56m
    $62–122

  5. Fly to Nashville, bus

    1. Fly from Cleveland-Hopkins International Airport (CLE) to Nashville (BNA)plane plane CLE - BNA
    2. Take the bus from Nashville Bus Station to Louisville Bus Stationbus bus
    7h 9m
    $118–350

Cleveland to Louisville, KY by bus

Calendar22Weekly Buses
Duration6h 50mAverage Duration
Ticket$35Cheapest Price
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Questions & Answers

Map of how to get from Cleveland to Louisville, KY.ExpandLaunch map view
  • Distance: 357.3 mi
  • Duration: 6h 50m

What companies run services between Cleveland, OH, USA and Louisville, KY, USA?

Barons Bus operates a bus from Cleveland Ohio Greyhound Station to Louisville, KY Bus Station twice daily. Tickets cost $35–80 and the journey takes 6h 50m. Jefferson Lines also services this route once daily. Alternatively, Southwest Airlines, Delta, and two other airlines fly from Cleveland-Hopkins International Airport (CLE) to Louisville International Airport (SDF) hourly.

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