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How to get fromCleveland to Mechanicsburgby bus (Greyhound, Flixbus), train (Amtrak), car, plane, train, or bus (Flixbus)

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There are 5 ways to get from Cleveland to Mechanicsburg by bus (Greyhound, Flixbus), train (Amtrak), car, plane, train, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus via Pittsburgh

    best
    1. Take the bus from Cleveland Bus Station to Pittsburgh Intermodal Stationbus bus Greyhound US0420 / ...
    2. Take the bus from Pittsburgh Intermodal Station to Harrisburg Bus Stationbus bus Greyhound US0421 / ...
    9h 35m
    $54–90

  2. Bus

    cheapest
    1. Take the bus from W. Prospect Ave & Superior Ave to Robert K Pfaff Transit Center - Akronbus bus 61
    2. Take the bus from Robert K Pfaff Transit Center - Akron to State College Regional Airportbus bus
    3. Take the bus from State College Regional Airport to Harrisburg Bus Stationbus bus
    10h 15m
    $45–74

  3. Train (Amtrak)

    1. Take the train from Cleveland Amtrak to Pittsburgh Amtrak Stationtrain train Floridian
    2. Take the train from Pittsburgh Amtrak Station to Harrisburgtrain train Pennsylvanian
    10h 40m
    $207–328

  4. Drive  316.7 mi

    1. Drive from Cleveland to Mechanicsburgcar car 316.7 mi
    5h 30m
    $58–84

  5. Fly, train

    1. Fly from Cleveland-Hopkins International Airport (CLE) to Philadelphia International Airport (PHL)plane plane CLE - PHL
    2. Take the train from 30th Street Station to Harrisburgtrain train
    7h 32m
    $230–528

Cleveland to Mechanicsburg by subway, foot, and bus

Calendar28Weekly Services
Duration9h 35mAverage Duration
Ticket$54Cheapest Price
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Comparing Your Travel Options

Map of how to get from Cleveland to Mechanicsburg.ExpandLaunch map view
  • Distance: 351.8 mi
  • Duration: 9h 35m

What companies run services between Cleveland, OH, USA and Mechanicsburg, Cumberland County, PA, USA?

You can take a subway from Tower City Station Track 8 to E Main St & Arch St WB via Brookpark Station, Cleveland Bus Station, Pittsburgh Intermodal Station, Harrisburg Bus Station, and Market Square Transfer Center in around 9h 35m. Alternatively, you can take a train from Cleveland Amtrak to E Main St & Arch St WB via Pittsburgh Amtrak Station, Harrisburg, and Market Square Transfer Center in around 10h 40m.

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