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How to get fromCleveland to Mount Pleasantby plane, train (Amtrak), car, bus, or train

Find Transport to Mount Pleasant

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There are 7 ways to get from Cleveland to Mount Pleasant by plane, train (Amtrak), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Cleveland-Hopkins International Airport to Charleston International Airport

    best
    1. Fly from Cleveland-Hopkins International Airport (CLE) to Charleston International Airport (CHS)plane plane CLE - CHS
    8h 20m
    $106–606

  2. Bus to Akron, fly to Charleston International Airport

    cheapest
    1. Take the bus from Cleveland to Akronbus bus
    2. Fly from Akron (CAK) to Charleston International Airport (CHS)plane plane CAK - CHS
    7h 50m
    $82–468

  3. Train (Amtrak)

    1. Take the train from Cleveland Amtrak to Petersburg Amtrak Stationtrain train Floridian
    2. Take the train from Petersburg Amtrak Station to Charleston Amtrak Stationtrain train Silver Meteor / ...
    22h 29m
    $551–837

  4. Drive  714.5 mi

    1. Drive from Cleveland to Mount Pleasantcar car 714.5 mi
    12h 14m
    $123–177

  5. Fly Cleveland-Hopkins International Airport to Charlotte Douglas International Airport, drive

    1. Fly from Cleveland-Hopkins International Airport (CLE) to Charlotte Douglas International Airport (CLT)plane plane CLE - CLT
    2. Drive from Charlotte-Airport-CLT to Mount Pleasantcar car
    6h 51m
    $148–808

  6. Train to Pittsburgh International Airport, fly to Charleston International Airport

    1. Take the train from Cleveland Amtrak to Pittsburgh Amtrak Stationtrain train
    2. Fly from Pittsburgh International Airport (PIT) to Charleston International Airport (CHS)plane plane PIT - CHS
    10h 30m
    $170–670

  7. Bus to Akron, fly to Charlotte Douglas International Airport, drive

    1. Take the bus from Cleveland to Akronbus bus
    2. Fly from Akron (CAK) to Charlotte Douglas International Airport (CLT)plane plane CAK - CLT
    3. Drive from Charlotte-Airport-CLT to Mount Pleasantcar car
    8h 36m
    $123–639

Cleveland-Hopkins International Airport (CLE) to Charleston International Airport (CHS) flights

Calendar109Weekly Planes
Duration4h 49mAverage Duration
Ticket$100Cheapest Price
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Comparing Your Travel Options

Map of how to get from Cleveland to Mount Pleasant.ExpandLaunch map view
  • Distance: 630.7 mi
  • Duration: 8h 20m

What companies run services between Cleveland, OH, USA and Mount Pleasant, SC, USA?

American Airlines, Southwest Airlines, and two other airlines fly from Cleveland-Hopkins International Airport (CLE) to Charleston International Airport (CHS) hourly. Alternatively, you can take a train from Cleveland Amtrak to Mount Pleasant via Petersburg Amtrak Station and Charleston Amtrak Station in around 22h 29m.

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