There are 5 ways to get from Cleveland to Orangeburg by plane, taxi, bus (Greyhound, Flixbus), train (Amtrak), car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Columbia, taxi
best- Fly from Cleveland-Hopkins International Airport (CLE) to Columbia (CAE)plane CLE - CAE
- Take the taxi from Columbia-Airport-CAE to Orangeburgtaxi
5h 44m$312–1,252Bus
cheapest- Take the bus from Cleveland, OH to Charleston, WVbus
- Take the bus from Charleston, WV to Charlotte Bus Stationbus
- Take the bus from Charlotte Bus Station to Orangeburgbus
16h 43m$99–206Train (Amtrak)
- Take the train from Cleveland Amtrak to Denmark Amtrak Stationtrain Floridian
24h 8m$390–726Drive 639.4 mi
- Drive from Cleveland to Orangeburgcar 639.4 mi
11h 2m$117–169Fly to Charlotte Douglas International Airport, bus
- Fly from Cleveland-Hopkins International Airport (CLE) to Charlotte Douglas International Airport (CLT)plane CLE - CLT
- Take the bus from Charlotte Bus Station to Orangeburgbus
9h$150–718
Cleveland-Hopkins International Airport (CLE) to Columbia (CAE) flights
Questions & Answers
The cheapest way to get from Cleveland to Orangeburg is to bus which costs $95 - $210 and takes 16h 43m.
The fastest way to get from Cleveland to Orangeburg is to fly and taxi which takes 5h 44m and costs $310 - $1,300.
No, there is no direct bus from Cleveland to Orangeburg. However, there are services departing from Cleveland, OH and arriving at Orangeburg via Charleston, WV and Charlotte Bus Station. The journey, including transfers, takes approximately 16h 43m.
No, there is no direct train from Cleveland to Orangeburg station. However, there are services departing from Cleveland Amtrak and arriving at Denmark Amtrak Station via . The journey, including transfers, takes approximately 24h 8m.
The distance between Cleveland and Orangeburg is 571 miles. The road distance is 643.2 miles.
The best way to get from Cleveland to Orangeburg without a car is to bus which takes 16h 43m and costs $95 - $210.
It takes approximately 5h 44m to get from Cleveland to Orangeburg, including transfers.
Cleveland to Orangeburg bus services, operated by Barons Bus, depart from Cleveland, OH station.
Cleveland to Orangeburg train services, operated by Amtrak, depart from Cleveland Amtrak station.
The best way to get from Cleveland to Orangeburg is to bus which takes 16h 43m and costs $95 - $210. Alternatively, you can train, which costs $390 - $750 and takes 24h 8m.
What companies run services between Cleveland, OH, USA and Orangeburg, SC, USA?
You can take a bus from Cleveland, OH to Orangeburg via Charleston, WV, Charlotte Bus Station, and Orangeburg in around 16h 43m. Alternatively, Amtrak operates a train from Cleveland Amtrak to Denmark Amtrak Station once daily. Tickets cost $320–650 and the journey takes 23h 36m.
- Website
- aa.com
Flights from Cleveland-Hopkins International Airport to Columbia via Charlotte Douglas International Airport
- Ave. Duration
- 4h 34m
- When
- Every day
- Estimated price
- $190–1,100
Flights from Cleveland-Hopkins International Airport to Columbia via Philadelphia
- Ave. Duration
- 5h 2m
- When
- Every day
- Estimated price
- $270–1,400
Flights from Cleveland-Hopkins International Airport to Columbia via Reagan Washington
- Ave. Duration
- 6h 9m
- When
- Monday, Tuesday, Wednesday, Thursday, and Sunday
- Estimated price
- $230–1,300
Flights from Cleveland-Hopkins International Airport to Columbia via New York La Guardia
- Ave. Duration
- 6h 26m
- When
- Monday to Thursday
- Estimated price
- $300–1,500
Flights from Cleveland-Hopkins International Airport to Columbia via Chicago O'Hare
- Ave. Duration
- 7h 10m
- When
- Every day
- Estimated price
- $290–1,400
Flights from Cleveland-Hopkins International Airport to Charlotte Douglas International Airport
- Ave. Duration
- 1h 43m
- When
- Every day
- Estimated price
- $110–650
Flights from Cleveland-Hopkins International Airport to Charlotte Douglas International Airport via Reagan Washington
- Ave. Duration
- 4h 6m
- When
- Tuesday, Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $130–750
- Website
- delta.com
Flights from Cleveland-Hopkins International Airport to Columbia via Atlanta
- Ave. Duration
- 4h 25m
- When
- Every day
- Estimated price
- $240–1,300
Flights from Cleveland-Hopkins International Airport to Columbia via New York La Guardia
- Ave. Duration
- 6h 12m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $300–1,500
Flights from Cleveland-Hopkins International Airport to Charlotte Douglas International Airport via Detroit
- Ave. Duration
- 3h 59m
- When
- Every day
- Estimated price
- $130–750
- Website
- united.com
Flights from Cleveland-Hopkins International Airport to Columbia via Washington Dulles
- Ave. Duration
- 4h
- When
- Every day
- Estimated price
- $230–1,200
Flights from Cleveland-Hopkins International Airport to Columbia via Chicago O'Hare
- Ave. Duration
- 4h 54m
- When
- Every day
- Estimated price
- $290–1,400
Flights from Cleveland-Hopkins International Airport to Charlotte Douglas International Airport via Washington Dulles
- Ave. Duration
- 3h 50m
- When
- Every day
- Estimated price
- $130–750
- Website
- southwest.com
Flights from Cleveland-Hopkins International Airport to Charlotte Douglas International Airport via Nashville
- Ave. Duration
- 3h 50m
- When
- Saturday
- Estimated price
- $150–800
Flights from Cleveland-Hopkins International Airport to Charlotte Douglas International Airport via Baltimore
- Ave. Duration
- 4h 5m
- When
- Saturday
- Estimated price
- $140–750
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Cleveland Amtrak to Denmark Amtrak Station
- Ave. Duration
- 23h 36m
- Frequency
- Once daily
- Estimated price
- $320–650
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 888-378-3823
- [email protected]
- Website
- baronsbus.com
Bus from Cleveland, OH to Charleston, WV
- Ave. Duration
- 5h 30m
- Frequency
- Once daily
- Estimated price
- $25–70
- Website
- https://baronsbus.com
Bus from Charleston, WV to Charlotte Bus Station
- Ave. Duration
- 5h 10m
- Frequency
- Once daily
- Estimated price
- $26–70
- Website
- https://baronsbus.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Charleston, WV to Charlotte Bus Station
- Ave. Duration
- 6h 30m
- Frequency
- Once daily
- Estimated price
- $40–80
- Website
- https://www.greyhound.com/
Bus from Charlotte Bus Station to Orangeburg
- Ave. Duration
- 4h
- Frequency
- Twice daily
- Estimated price
- $26–50
- Website
- https://www.greyhound.com/
Bus from Charlotte Bus Station to Orangeburg
- Ave. Duration
- 4h
- Frequency
- Twice daily
- Estimated price
- $26–50
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Charlotte Bus Station to Orangeburg
- Ave. Duration
- 2h 35m
- Frequency
- Once daily
- Estimated price
- $26–45
- Schedules at
- flixbus.com
Bus from Charlotte Bus Station to Orangeburg
- Ave. Duration
- 2h 35m
- Frequency
- Once daily
- Estimated price
- $26–45
- Schedules at
- flixbus.com
- Ave. Duration
- 42 min
- Estimated price
- $120–150
Checker Yellow Cabs
- Phone
- +1 803-799-3311
- Website
- checkeryellowcab.com
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More Questions & Answers
Cleveland to Orangeburg bus services, operated by Barons Bus, arrive at Charleston, WV station.
Cleveland to Orangeburg train services, operated by Amtrak, arrive at Denmark Amtrak Station.
Yes, the driving distance between Cleveland to Orangeburg is 643 miles. It takes approximately 11h 2m to drive from Cleveland to Orangeburg.
Book your Cleveland to Orangeburg bus tickets online with Omio.
There are 22+ hotels available in Orangeburg.










