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How to get fromCleveland to Orangeburgby plane, taxi, bus (Flixbus, Greyhound), train (Amtrak), car, or bus

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There are 6 ways to get from Cleveland to Orangeburg by plane, taxi, bus (Flixbus, Greyhound), train (Amtrak), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Cleveland-Hopkins International Airport to Columbia, taxi

    best
    1. Fly from Cleveland-Hopkins International Airport (CLE) to Columbia (CAE)plane plane CLE - CAE
    2. Take the taxi from Columbia-Airport-CAE to Orangeburgtaxi taxi
    5h 49m
    $198–612

  2. Bus

    cheapest
    1. Take the bus from Cleveland to Charlestonbus bus
    2. Take the bus from Charleston to Charlottebus bus
    3. Take the bus from Charlotte Bus Station to Orangeburgbus bus
    15h 18m
    $80–185

  3. Train (Amtrak)

    1. Take the train from Cleveland Amtrak to Denmark Amtrak Stationtrain train Floridian
    24h 8m
    $606–910

  4. Drive  639.4 mi

    1. Drive from Cleveland to Orangeburgcar car 639.4 mi
    10h 59m
    $117–169

  5. Bus to Akron, fly to Charleston International Airport, drive

    1. Take the bus from Cleveland to Akronbus bus
    2. Fly from Akron (CAK) to Charleston International Airport (CHS)plane plane CAK - CHS
    3. Drive from Charleston-Airport-CHS to Orangeburgcar car
    6h 5m
    $95–513

  6. Fly Cleveland-Hopkins International Airport to Charlotte Douglas International Airport, bus

    1. Fly from Cleveland-Hopkins International Airport (CLE) to Charlotte Douglas International Airport (CLT)plane plane CLE - CLT
    2. Take the bus from Charlotte Bus Station to Orangeburgbus bus
    7h 34m
    $146–758

Cleveland-Hopkins International Airport (CLE) to Columbia (CAE) flights

Calendar113Weekly Planes
Duration5h 8mAverage Duration
Ticket$78Cheapest Price
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Comparing Your Travel Options

Map of how to get from Cleveland to Orangeburg.ExpandLaunch map view
  • Distance: 568 mi
  • Duration: 5h 49m

What companies run services between Cleveland, OH, USA and Orangeburg, SC, USA?

You can take a bus from Cleveland to Orangeburg via Charleston, Charlotte Bus Station, and Orangeburg in around 15h 18m. Alternatively, Amtrak operates a train from Cleveland Amtrak to Denmark Amtrak Station once daily. Tickets cost $500–850 and the journey takes 23h 36m.

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