There are 4 ways to get from Cleveland to Saint Charles by plane, bus (Greyhound), train (Amtrak), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Cleveland-Hopkins International Airport (CLE) to Lambert–St. Louis International Airport (STL)plane CLE - STL
4h 9m$496–906Bus
cheapest- Take the bus from Cleveland Ohio Greyhound Station to Columbus - Downtown - Mound Stbus Cleveland
- Take the bus from Columbus to St Louis Bus Stationbus Greyhound US0421
13h 45m$83–183Train (Amtrak)
- Take the train from Cleveland Amtrak to Chicago Union Stationtrain Floridian / ...
- Take the train from Chicago Union Station to St. Louistrain Lincoln Service / ...
13h 57m$206–415Drive 567.1 mi
- Drive from Cleveland to Saint Charlescar 567.1 mi
9h 40m$104–150
Cleveland to Saint Charles by bus and train
Questions & Answers
The cheapest way to get from Cleveland to Saint Charles is to bus which costs $80 - $190 and takes 13h 45m.
The fastest way to get from Cleveland to Saint Charles is to fly which takes 4h 9m and costs $490 - $950.
No, there is no direct bus from Cleveland station to Saint Charles. However, there are services departing from Cleveland Ohio Greyhound Station and arriving at 4375 Rider Trail North Sb via Columbus and North Hanley Transit Center. The journey, including transfers, takes approximately 13h 45m.
No, there is no direct train from Cleveland to Saint Charles station. However, there are services departing from Cleveland Amtrak and arriving at NORTH HANLEY station via Chicago Union Station and CIVIC CENTER station. The journey, including transfers, takes approximately 13h 57m.
The distance between Cleveland and Saint Charles is 515 miles. The road distance is 570.4 miles.
The best way to get from Cleveland to Saint Charles without a car is to bus which takes 13h 45m and costs $80 - $190.
It takes approximately 4h 9m to get from Cleveland to Saint Charles, including transfers.
Cleveland to Saint Charles bus services, operated by Barons Bus, depart from Cleveland Ohio Greyhound Station.
Cleveland to Saint Charles train services, operated by Amtrak, depart from Cleveland Amtrak station.
The best way to get from Cleveland to Saint Charles is to fly which takes 4h 9m and costs $490 - $950. Alternatively, you can bus, which costs $80 - $190 and takes 13h 45m, you could also train, which costs $200 - $420 and takes 13h 57m.
What companies run services between Cleveland, OH, USA and Saint Charles, MO, USA?
Southwest Airlines, Delta, and United Airlines fly from Cleveland-Hopkins International Airport (CLE) to Lambert–St. Louis International Airport (STL) every 4 hours. Alternatively, you can take a bus from Cleveland Ohio Greyhound Station to 4375 Rider Trail North Sb via Columbus, St Louis Bus Station, CIVIC CENTER station, NORTH HANLEY station, and North Hanley Transit Center in around 13h 45m.
- Website
- southwest.com
Flights from Cleveland-Hopkins International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- $110–700
Flights from Cleveland-Hopkins International Airport to Lambert–St. Louis International Airport via Chicago Midway
- Ave. Duration
- 3h 22m
- When
- Every day
- Estimated price
- $120–700
Flights from Cleveland-Hopkins International Airport to Lambert–St. Louis International Airport via Nashville
- Ave. Duration
- 3h 40m
- When
- Sunday
- Estimated price
- $150–800
- Website
- delta.com
Flights from Cleveland-Hopkins International Airport to Lambert–St. Louis International Airport via Detroit
- Ave. Duration
- 3h 52m
- When
- Every day
- Estimated price
- $120–700
- Website
- united.com
Flights from Cleveland-Hopkins International Airport to Lambert–St. Louis International Airport via Chicago O'Hare
- Ave. Duration
- 4h 3m
- When
- Every day
- Estimated price
- $130–700
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Cleveland Amtrak to Chicago Union Station
- Ave. Duration
- 6h 46m
- Frequency
- 3 times a day
- Estimated price
- $110–230
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to St. Louis
- Ave. Duration
- 4h 46m
- Frequency
- 5 times a day
- Estimated price
- $90–190
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 888-378-3823
- [email protected]
- Website
- baronsbus.com
Bus from Cleveland Ohio Greyhound Station to Columbus - Downtown - Mound St
- Ave. Duration
- 2h 15m
- Frequency
- Twice daily
- Estimated price
- $13–50
- Website
- https://baronsbus.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Columbus to St Louis Bus Station
- Ave. Duration
- 9h 5m
- Frequency
- 3 times a day
- Estimated price
- $65–130
- Website
- https://www.greyhound.com/
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More Questions & Answers
Cleveland to Saint Charles bus services, operated by Barons Bus, arrive at Columbus - Downtown - Mound St station.
Saint Charles is 1h behind Cleveland. It is currently 4:48 PM in Cleveland and 3:48 PM in Saint Charles.
Cleveland to Saint Charles train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Cleveland to Saint Charles is 570 miles. It takes approximately 9h 40m to drive from Cleveland to Saint Charles.
There are 200+ hotels available in Saint Charles.