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How to get fromCleveland to Saint Charlesby plane, bus, train (Amtrak), car, or train

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There are 7 ways to get from Cleveland to Saint Charles by plane, bus, train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Cleveland-Hopkins International Airport to Chicago O'Hare International Airport, bus

    best
    1. Fly from Cleveland-Hopkins International Airport (CLE) to Chicago O'Hare International Airport (ORD)plane plane CLE - ORD
    2. Take the bus from Rosemont CTA Station to Elgin Transportation Center Bay 4bus bus
    4h 44m
    $406–856

  2. Drive 375.9 mi

    cheapest
    1. Drive from Cleveland to Saint Charlescar car 375.9 mi
    6h 40m
    $69–100

  3. Train

    1. Take the train from Cleveland Amtrak to Chicago Union Stationtrain train Floridian / ...
    2. Take the train from Chicago OTC to Genevatrain train Up-W
    8h 43m
    $130–249

  4. Bus

    1. Take the bus from Cleveland to Chicagobus bus Cleveland
    2. Take the bus from Rosemont CTA Station to Elgin Transportation Center Bay 4bus bus 603
    10h 49m
    $72–140

  5. Fly Cleveland-Hopkins International Airport to Chicago Midway International Airport, train

    1. Fly from Cleveland-Hopkins International Airport (CLE) to Chicago Midway International Airport (MDW)plane plane CLE - MDW
    2. Take the train from Chicago OTC to Genevatrain train
    5h 20m
    $82–410

  6. Bus to Akron, fly to Chicago O'Hare International Airport, bus

    1. Take the bus from Cleveland, OH to Robert K Pfaff Transit Center - Akronbus bus
    2. Fly from Akron (CAK) to Chicago O'Hare International Airport (ORD)plane plane CAK - ORD
    3. Take the bus from Rosemont CTA Station to Elgin Transportation Center Bay 4bus bus
    6h 42m
    $77–348

  7. Bus, train

    1. Take the bus from Cleveland Bus Station to Chicago Bus Stationbus bus Greyhound US0164
    2. Take the train from Chicago OTC to Genevatrain train Up-W
    11h 27m
    $72–128

Cleveland-Hopkins International Airport (CLE) to Chicago O'Hare International Airport (ORD) flights

Calendar122Weekly Planes
Duration1h 59mAverage Duration
Ticket$51Cheapest Price
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Questions & Answers

Map of how to get from Cleveland to Saint Charles.ExpandLaunch map view
  • Distance: 365.2 mi
  • Duration: 4h 44m

What companies run services between Cleveland, OH, USA and Saint Charles, IL, USA?

You can take a train from Cleveland Amtrak to Saint Charles via Chicago Union Station, Washington & Jefferson, Washington & Canal, Chicago OTC, and Geneva in around 8h 43m. Alternatively, you can take a bus from Cleveland to Saint Charles via Chicago Bus Station, Chicago, Cumberland, Rosemont, Rosemont CTA Station, and Elgin Transportation Center Bay 4 in around 10h 49m.

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