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How to get fromCleveland to Sanibel Islandby plane, bus (Greyhound, Flixbus), train, bus, or car

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There are 5 ways to get from Cleveland to Sanibel Island by plane, bus (Greyhound, Flixbus), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Cleveland-Hopkins International Airport

    best
    1. Fly from Cleveland-Hopkins International Airport (CLE) to Ft. Myers (RSW)plane plane CLE - RSW
    4h 48m
    $268–738
  2. Bus to Akron, fly

    cheapest
    1. Take the bus from Cleveland to Akronbus bus
    2. Fly from Akron (CAK) to Ft. Myers (RSW)plane plane CAK - RSW
    6h 30m
    $178–719
  3. Bus

    1. Take the bus from Cleveland to Toledobus bus
    2. Take the bus from Toledo Bus Stop to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Tampa Bus Stationbus bus
    4. Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus bus
    33h 28m
    $281–463
  4. Train, bus

    1. Take the train from Cleveland Amtrak to Tampatrain train Floridian
    2. Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus bus FlixBus 2421
    38h 41m
    $879–1,329
  5. Drive  1,194.8 mi

    1. Drive from Cleveland to Sanibel Islandcar car 1,194.8 mi
    20h 50m
    $205–295

Cleveland-Hopkins International Airport (CLE) to Ft. Myers (RSW) flights

Calendar80Weekly Planes
Duration4h 39mAverage Duration
Ticket$153Cheapest Price
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Comparing Your Travel Options

What companies run services between Cleveland, OH, USA and Sanibel Island, FL, USA?

Frontier Airlines, United Airlines, and two other airlines fly from Cleveland-Hopkins International Airport (CLE) to Ft. Myers (RSW) every 2 hours. Alternatively, you can take a bus from Cleveland to Sanibel Island via Toledo Bus Stop, Atlanta Bus Station, Tampa Bus Station, Rosa Parks Transportation Ctr, and Cape Coral Transfer Center in around 33h 28m.

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Want to know more about travelling around United States

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Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There