There are 7 ways to get from Cleveland to Santee by bus, plane, car, bus (Greyhound, Flixbus), train, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Akron, fly to Charleston International Airport, drive
best- Take the bus from Cleveland to Akronbus
- Fly from Akron (CAK) to Charleston International Airport (CHS)plane CAK - CHS
- Drive from Charleston-Airport-CHS to Santeecar
6h 1m$83–450Bus
- Take the bus from Cleveland, OH to Charleston, WVbus
- Take the bus from Charleston, WV to Charlotte Bus Stationbus
- Take the bus from Charlotte Bus Station to Orangeburgbus
17h 8m$169–281Train, taxi (Amtrak)
- Take the train from Cleveland Amtrak to Denmark Amtrak Stationtrain Floridian
- Take the taxi from Denmark Amtrak Station to Santeetaxi
24h 33m$401–752Drive 658.3 mi
- Drive from Cleveland to Santeecar 658.3 mi
11h 17m$121–174Train to Pittsburgh International Airport, fly to Charleston International Airport, drive
- Take the train from Cleveland Amtrak to Pittsburgh Amtrak Stationtrain
- Fly from Pittsburgh International Airport (PIT) to Charleston International Airport (CHS)plane PIT - CHS
- Drive from Charleston-Airport-CHS to Santeecar
8h 36m$137–646Fly Cleveland-Hopkins International Airport to Charlotte Douglas International Airport, bus
- Fly from Cleveland-Hopkins International Airport (CLE) to Charlotte Douglas International Airport (CLT)plane CLE - CLT
- Take the bus from Charlotte Bus Station to Orangeburgbus
9h 22m$210–754Bus to Akron, fly to Savannah, train, taxi
- Take the bus from Cleveland to Akronbus
- Fly from Akron (CAK) to Savannah (SAV)plane CAK - SAV
- Take the train from Savannah Station to Denmark Amtrak Stationtrain
- Take the taxi from Denmark Amtrak Station to Santeetaxi
8h 26m$296–869
Akron (CAK) to Charleston International Airport (CHS) flights
Questions & Answers
The cheapest way to get from Cleveland to Santee is to drive which costs $120 - $180 and takes 11h 17m.
The fastest way to get from Cleveland to Santee is to bus and fly and drive which takes 6h 1m and costs $80 - $450.
No, there is no direct bus from Cleveland to Santee. However, there are services departing from Cleveland, OH and arriving at Orangeburg via Charleston, WV and Charlotte Bus Station. The journey, including transfers, takes approximately 17h 8m.
The distance between Cleveland and Santee is 673 miles. The road distance is 662.1 miles.
The best way to get from Cleveland to Santee without a car is to bus which takes 17h 8m and costs $160 - $290.
It takes approximately 6h 1m to get from Cleveland to Santee, including transfers.
Cleveland to Santee bus services, operated by Barons Bus, depart from Cleveland, OH station.
Cleveland to Santee bus services, operated by Barons Bus, arrive at Charleston, WV station.
Yes, the driving distance between Cleveland to Santee is 662 miles. It takes approximately 11h 17m to drive from Cleveland to Santee.
There are 42+ hotels available in Santee.
What companies run services between Cleveland, OH, USA and Santee, SC, USA?
You can take a bus from Cleveland, OH to Santee via Charleston, WV, Charlotte Bus Station, and Orangeburg in around 17h 8m.
- Website
- aa.com
Flights from Akron to Charleston International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h
- When
- Every day
- Estimated price
- $70–400
Flights from Pittsburgh International Airport to Charleston International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 3h 39m
- When
- Every day
- Estimated price
- $90–550
Flights from Cleveland-Hopkins International Airport to Charlotte Douglas International Airport
- Ave. Duration
- 1h 41m
- When
- Every day
- Estimated price
- $100–600
Flights from Akron to Savannah via Charlotte Douglas International Airport
- Ave. Duration
- 4h 13m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $90–550
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Cleveland Amtrak to Denmark Amtrak Station
- Ave. Duration
- 23h 36m
- Frequency
- Once daily
- Estimated price
- $260–600
- Website
- Amtrak
Train from Cleveland Amtrak to Pittsburgh Amtrak Station
- Ave. Duration
- 3h 11m
- Frequency
- Once daily
- Estimated price
- $35–80
- Website
- Amtrak
Train from Savannah Station to Denmark Amtrak Station
- Ave. Duration
- 1h 21m
- Frequency
- Once daily
- Estimated price
- $23–55
- Website
- Amtrak
- Phone
- +1 888-378-3823
- [email protected]
- Website
- Barons Bus
Bus from Cleveland to Akron
- Ave. Duration
- 45 min
- Frequency
- 3 times a day
- Estimated price
- $3–35
- Website
- Barons Bus
Bus from Cleveland, OH to Charleston, WV
- Ave. Duration
- 5h 30m
- Frequency
- Twice daily
- Estimated price
- $25–70
- Website
- Barons Bus
Bus from Charleston, WV to Charlotte Bus Station
- Ave. Duration
- 5h 10m
- Frequency
- Twice daily
- Estimated price
- $26–70
- Website
- Barons Bus
Bus from Cleveland to Akron
- Ave. Duration
- 45 min
- Frequency
- 3 times a day
- Estimated price
- $3–35
- Website
- Barons Bus
- Ave. Duration
- 57 min
- Estimated price
- $140–180
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