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How to get fromColón to Santiagoby bus, car, taxi, or plane

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There are 6 ways to get from Colón to Santiago by bus, car, taxi, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Colón to Panama Citybus bus Panama
    2. Take the bus from Panama City to Santiagobus bus David
    4h 58m
    $11–22

  2. Drive 249.1 km

    1. Drive from Colón to Santiagocar car 249.1 km
    5h 29m
    $35–50

  3. Taxi

    1. Take the taxi from Colón to Santiagotaxi taxi 249.1 km
    5h 29m
    $130–170

  4. Bus, fly

    1. Take the bus from Colón to Panama Citybus bus
    2. Fly from Albrook Marcos A. Gelabert International Airport (PAC) to Chitre (CTD)plane plane PAC - CTD
    3. Take the bus from Chitré to Ocubus bus
    4. Take the bus from Ocu to Santiagobus bus
    5h 19m
    $148–157

  5. Bus via Penonomé

    1. Take the bus from Colón to Panama Citybus bus
    2. Take the bus from Panama Albrook to Penonomébus bus
    3. Take the bus from Penonomé to Santiago de Veraguasbus bus
    5h 47m
    $20–31

  6. Bus via Santiago

    1. Take the bus from Colón to Panama Citybus bus Panama
    2. Take the bus from Albrook to Santiagobus bus Panama City
    6h 24m
    $15–17

Albrook Marcos A. Gelabert International Airport (PAC) to Chitre (CTD) flights

Calendar4Weekly Planes
Duration30 minAverage Duration
Ticket$29Cheapest Price
See schedules

Questions & Answers

Map of how to get from Colón to Santiago.ExpandLaunch map view
  • Distance: 322.7 km
  • Duration: 4h 58m

What companies run services between Colón, Panama and Santiago, Panama?

You can take a bus from Colón to Santiago via Panama City in around 4h 58m.

Airlines
Bus operators
Other operators

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