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How to get fromColorado to San Diegoby plane, bus (Greyhound, Flixbus), bus, train, car, or bus (Greyhound)

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There are 6 ways to get from Colorado to San Diego by plane, bus (Greyhound, Flixbus), bus, train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Colorado Springs Airport

    best
    1. Fly from Colorado Springs Airport (COS) to San Diego International Airport (SAN)plane plane COS - SAN
    4h 36m
    $79–404
  2. Bus via Santa Ana

    1. Take the bus from Denver Union Station to Las Vegas Bus Terminalbus bus
    2. Take the bus from Las Vegas Bus Terminal to Santa Ana Bus Stopbus bus
    3. Take the bus from Santa Ana Bus Stop to San Diegobus bus
    25h 58m
    $166–284
  3. Bus, train

    1. Take the bus from Denver to Las Vegas Transportation Centerbus bus
    2. Take the train from Las Vegas Amtrak Station to Fullerton Amtrak Stationtrain train
    3. Take the train from Fullerton Amtrak Station to San Diegotrain train
    29h 38m
    $360–751
  4. Drive  1,078.6 mi

    1. Drive from Denver to San Diegocar car 1,078.6 mi
    16h 54m
    $197–285
  5. Fly from Denver

    1. Fly from Denver (DEN) to San Diego International Airport (SAN)plane plane DEN - SAN
    4h 32m
    $126–216
  6. Bus (Greyhound)

    1. Take the bus from Denver Union Station to Las Vegas Bus Terminalbus bus Greyhound US1200
    2. Take the bus from Las Vegas Bus Terminal to San Diego Greyhound Bus Stopbus bus Greyhound US0901
    26h 11m
    $173–288

Colorado to San Diego by bus

Calendar7Weekly Buses
Duration25h 58mAverage Duration
Ticket$166Cheapest Price
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Questions & Answers

What companies run services between Colorado, USA and San Diego, CA, USA?

Southwest Airlines and United Airlines fly from Colorado Springs Airport (COS) to San Diego International Airport (SAN) every 4 hours. Alternatively, you can take a bus from Colfax Ave & Grant St to San Diego via Denver Union Station, Las Vegas Bus Terminal, and Santa Ana Bus Stop in around 25h 58m.

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Need to know: Greyhound

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