Rome2Rio

How to get fromColumbia to St. Louisby taxi, bus, car, or plane

Find Transport to St. Louis

See all options

There are 9 ways to get from Columbia to St. Louis by taxi, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi, bus via Indianapolis (Greyhound)

    best
    1. Take the taxi from Columbia to Uptontaxi taxi
    2. Take the bus from Upton to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to St Louis Bus Stationbus bus
    10h 5m
    $206–291

  2. Drive 339.1 mi

    cheapest
    1. Drive from Columbia to St. Louiscar car 339.1 mi
    6h 3m
    $62–90

  3. Drive to Blue Grass Airport, fly

    1. Drive from Columbia to Lexington-Airport-LEXcar car
    2. Fly from Blue Grass Airport (LEX) to Lambert–St. Louis International Airport (STL)plane plane LEX - STL
    6h 55m
    $161–828

  4. Taxi, bus

    1. Take the taxi from Columbia to Shell gas station - Cave Citytaxi taxi
    2. Take the bus from Shell gas station - Cave City to Tornado Bus Co - Nashvillebus bus
    3. Take the bus from Nashville Bus Station to St Louis Bus Stationbus bus
    11h 4m
    $218–386

  5. Taxi, bus #2

    1. Take the taxi from Columbia to Uptontaxi taxi
    2. Take the bus from Upton to Nashville Bus Stationbus bus
    3. Take the bus from Nashville Bus Station to St Louis Bus Stationbus bus
    11h 5m
    $207–296

  6. Taxi, bus #3

    1. Take the taxi from Columbia to Shell gas station - Cave Citytaxi taxi
    2. Take the bus from Shell gas station - Cave City to Tornado Bus Co - Nashvillebus bus
    3. Take the bus from Nashville Bus Station to Carbondale Intermodal Stationbus bus
    4. Take the bus from Carbondale Intermodal Station to St Louis Bus Stationbus bus
    11h 14m
    $218–396

  7. Drive to Mcghee Tyson Airport, fly

    1. Drive from Columbia to Mcghee Tyson Airport (TYS)car car
    2. Fly from Mcghee Tyson Airport (TYS) to Lambert–St. Louis International Airport (STL)plane plane TYS - STL
    7h 32m
    $141–743

  8. Taxi, bus to Nashville, fly

    1. Take the taxi from Columbia to Uptontaxi taxi
    2. Take the bus from Upton to Nashville Bus Stationbus bus
    3. Fly from Nashville (BNA) to Lambert–St. Louis International Airport (STL)plane plane BNA - STL
    6h 57m
    $247–811

  9. Taxi, bus to Louisville International Airport, fly

    1. Take the taxi from Columbia to Shell gas station - Cave Citytaxi taxi
    2. Take the bus from Shell gas station - Cave City to La Tropicana - Louisville, KYbus bus
    3. Fly from Louisville International Airport (SDF) to Lambert–St. Louis International Airport (STL)plane plane SDF - STL
    9h 48m
    $269–891

Blue Grass Airport (LEX) to Lambert–St. Louis International Airport (STL) flights

Calendar115Weekly Planes
Duration5h 39mAverage Duration
Ticket$146Cheapest Price
See schedules

Questions & Answers

Map of how to get from Columbia to St. Louis.ExpandLaunch map view
  • Distance: 467.4 mi
  • Duration: 10h 5m

What companies run services between Columbia, KY, USA and St. Louis, MO, USA?

There is no direct connection from Columbia to St. Louis. However, you can take the taxi to Upton, take the bus to Indianapolis Union Station, then take the bus to St Louis Bus Station. Alternatively, you can drive from Columbia to St. Louis in around 6h 3m.

Airlines
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound