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How to get fromColumbia to Florenceby bus, train, bus (Greyhound, Flixbus), car, plane, or subway

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There are 11 ways to get from Columbia to Florence by bus, train, bus (Greyhound, Flixbus), car, plane, or subway

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, train

    best
    1. Take the bus from LITTLE PATUXENT PKWY & VANTAGE POINT RD nb to 13TH ST & H ST NW sbbus bus 325
    2. Take the train from Alexandria to Florence Stationtrain train Palmetto / ...
    10h 5m
    $124–275

  2. Bus

    cheapest
    1. Take the bus from LITTLE PATUXENT PKWY & VANTAGE POINT RD nb to 13TH ST & H ST NW sbbus bus 325
    2. Take the bus from Washington Union Station to Raleigh Bus Stationbus bus
    3. Take the bus from Raleigh Bus Station to Florence Bus Stationbus bus
    11h 4m
    $62–125

  3. Drive 426.6 mi

    1. Drive from Columbia to Florencecar car 426.6 mi
    7h 26m
    $78–113

  4. Fly Baltimore-Washington International Airport to Charleston International Airport, train

    1. Fly from Baltimore-Washington International Airport (BWI) to Charleston International Airport (CHS)plane plane BWI - CHS
    2. Take the train from Charleston Amtrak Station to Florence Stationtrain train
    8h 57m
    $430–1,276

  5. Bus, train via Fayetteville

    1. Take the bus from COLUMBIA MALL & SOUTH RING RD eb to CONSTITUTION AVE & 10TH ST NW fs ebbus bus 305 / ...
    2. Take the bus from Washington Union Station to Fayetteville Bus Stationbus bus
    3. Take the train from Fayetteville Amtrak Station to Florence Stationtrain train
    12h 15m
    $80–145

  6. Fly Baltimore-Washington International Airport to Charlotte Douglas International Airport, bus

    1. Fly from Baltimore-Washington International Airport (BWI) to Charlotte Douglas International Airport (CLT)plane plane BWI - CLT
    2. Take the bus from Charlotte Bus Station to Camdenbus bus
    3. Take the bus from Camden to Florence Bus Stationbus bus
    9h 25m
    $124–370

  7. Fly Baltimore-Washington International Airport to Raleigh-Durham International Airport, bus

    1. Fly from Baltimore-Washington International Airport (BWI) to Raleigh-Durham International Airport (RDU)plane plane BWI - RDU
    2. Take the bus from Raleigh Bus Station to Florence Bus Stationbus bus
    9h 43m
    $214–407

  8. Bus to Ronald Reagan Washington National Airport, fly to Columbia, bus

    1. Take the bus from LITTLE PATUXENT PKWY & VANTAGE POINT RD nb to 13TH ST & H ST NW sbbus bus
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Columbia (CAE)plane plane DCA - CAE
    3. Take the bus from Columbia, SC to Camdenbus bus
    4. Take the bus from Camden to Florence Bus Stationbus bus
    10h 4m
    $134–614

  9. Fly Baltimore-Washington International Airport to Myrtle Beach, bus, train

    1. Fly from Baltimore-Washington International Airport (BWI) to Myrtle Beach (MYR)plane plane BWI - MYR
    2. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus bus
    3. Take the train from Charleston Amtrak Station to Florence Stationtrain train
    9h 57m
    $291–714

  10. Bus to Ronald Reagan Washington National Airport, fly to Myrtle Beach, bus, train

    1. Take the bus from LITTLE PATUXENT PKWY & VANTAGE POINT RD nb to 13TH ST & H ST NW sbbus bus
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Myrtle Beach (MYR)plane plane DCA - MYR
    3. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus bus
    4. Take the train from Charleston Amtrak Station to Florence Stationtrain train
    10h 10m
    $134–583

  11. Bus, subway to Washington Dulles International Airport, fly to Myrtle Beach, train

    1. Take the bus from LITTLE PATUXENT PKWY & VANTAGE POINT RD nb to 13TH ST & H ST NW sbbus bus
    2. Take the subway from Metro Center, Blue/Orange/Silver Line Center Platform to Washington Dulles International Airport, Silver Line Center Platformsubway subway
    3. Fly from Washington Dulles International Airport (IAD) to Myrtle Beach (MYR)plane plane IAD - MYR
    4. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus bus
    5. Take the train from Charleston Amtrak Station to Florence Stationtrain train
    12h 28m
    $108–412

Columbia to Florence by bus, subway, and train

Calendar5Weekly Services
Duration10h 5mAverage Duration
Ticket$124Cheapest Price
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Questions & Answers

Map of how to get from Columbia to Florence.ExpandLaunch map view
  • Distance: 436.3 mi
  • Duration: 10h 5m

What companies run services between Columbia, MD, USA and Florence, SC, USA?

You can take a bus from LITTLE PATUXENT PKWY & VANTAGE POINT RD nb to Florence Bus Station via 13TH ST & H ST NW sb, 13 St NW+G St NW, Massachusetts Av NE+1 St NE, Washington Union Station, and Raleigh Bus Station in around 11h 4m.

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