There are 5 ways to get from Columbia to Chicago Bus Station by plane, taxi, train, bus (Greyhound, Flixbus), car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Columbia Regional Airport (COU) to Chicago O'Hare International Airport (ORD)plane COU - ORD
2h 49m$97–331Bus
cheapest- Take the bus from Columbia to St Louis Bus Stationbus Greyhound US0175s
- Take the bus from St Louis Bus Station to Chicago Bus Stationbus FlixBus 2510 / ...
10h 40m$68–124Taxi, train
- Take the taxi from Columbia to Jefferson City Stationtaxi
- Take the train from Jefferson City Station to Chicago Union Stationtrain Lincoln Service Missouri River Runner
8h 54m$243–415Drive 378.3 mi
- Drive from Columbia to Chicago Bus Stationcar 378.3 mi
6h 53m$69–100Bus, train
- Take the bus from Columbia to St Louis Bus Stationbus Greyhound US0175s
- Take the train from St. Louis to Chicago Union Stationtrain Lincoln Service / ...
9h 39m$108–234
Columbia to Chicago Bus Station by bus
Questions & Answers
The cheapest way to get from Columbia to Chicago Bus Station is to bus which costs $65 - $130 and takes 10h 40m.
The fastest way to get from Columbia to Chicago Bus Station is to fly which takes 2h 49m and costs $95 - $340.
No, there is no direct bus from Columbia to Chicago Bus Station station. However, there are services departing from Columbia and arriving at Chicago Bus Station via St Louis Bus Station. The journey, including transfers, takes approximately 10h 40m.
The distance between Columbia and Chicago Bus Station is 350 miles. The road distance is 380.5 miles.
The best way to get from Columbia to Chicago Bus Station without a car is to taxi and train which takes 8h 54m and costs $240 - $420.
It takes approximately 2h 49m to get from Columbia to Chicago Bus Station, including transfers.
Columbia to Chicago Bus Station bus services, operated by Greyhound USA, depart from Columbia station.
The best way to get from Columbia to Chicago Bus Station is to fly which takes 2h 49m and costs $95 - $340. Alternatively, you can bus, which costs $65 - $130 and takes 10h 40m.
Columbia to Chicago Bus Station bus services, operated by Greyhound USA, arrive at St Louis Bus Station.
Yes, the driving distance between Columbia to Chicago Bus Station is 380 miles. It takes approximately 6h 53m to drive from Columbia to Chicago Bus Station.
What companies run services between Columbia, MO, USA and Chicago Bus Station, IL, USA?
American Airlines and United Airlines fly from Columbia Regional Airport (COU) to Chicago O'Hare International Airport (ORD) every 4 hours. Alternatively, you can take a bus from Columbia to Chicago Bus Station via St Louis Bus Station in around 10h 40m.
- Website
- aa.com
Flights from Columbia Regional Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 42m
- When
- Every day
- Estimated price
- $40–260
- Website
- united.com
Flights from Columbia Regional Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 43m
- When
- Every day
- Estimated price
- $40–260
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Jefferson City Station to Chicago Union Station
- Ave. Duration
- 8h 11m
- Frequency
- Once daily
- Estimated price
- $120–270
- Website
- Amtrak
Train from St. Louis to Chicago Union Station
- Ave. Duration
- 4h 55m
- Frequency
- 5 times a day
- Estimated price
- $85–190
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Columbia to St Louis Bus Station
- Ave. Duration
- 3h 35m
- Frequency
- Twice daily
- Estimated price
- $23–45
- Website
- Greyhound
Bus from Columbia to St Louis Bus Station
- Ave. Duration
- 3h 35m
- Frequency
- Twice daily
- Estimated price
- $23–45
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from St Louis Bus Station to Chicago Bus Station
- Ave. Duration
- 6h 5m
- Frequency
- Twice daily
- Estimated price
- $45–80
- Schedules at
- Flixbus USA
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
More Questions & Answers
Book your Columbia to Chicago Bus Station bus tickets online with Omio and FlixBus.
There are 1080+ hotels available in Chicago Bus Station.







