There are 5 ways to get from Columbia to Des Moines by bus (Greyhound), car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus via Columbia (Greyhound)
best- Take the bus from Columbia to Kansas City Bus Stationbus Greyhound US1200 / ...
- Take the bus from Kansas City Bus Station to Des Moinesbus Greyhound US0156
6h 8m$76–129Drive 225.2 mi
cheapest- Drive from Columbia to Des Moinescar 225.2 mi
4h 43m$42–60Fly
- Fly from Columbia Regional Airport (COU) to Des Moines (DSM)plane COU - DSM
4h 38m$182–737Bus (Greyhound)
- Take the bus from Columbia to Kansas City Bus Stationbus Greyhound US0175s
- Take the bus from Kansas City Bus Station to Des Moinesbus Greyhound US0156
6h 55m$48–96Bus #2
- Take the bus from Columbia to Kansas City Bus Stationbus Greyhound US0175s
- Take the bus from Kansas City to Des Moinesbus Jefferson Lines 804 / ...
7h 10m$69–111
Columbia to Des Moines by bus (Greyhound)
Questions & Answers
The cheapest way to get from Columbia to Des Moines is to drive which costs $40 - $60 and takes 4h 43m.
The fastest way to get from Columbia to Des Moines is to fly which takes 4h 38m and costs $180 - $750.
No, there is no direct bus from Columbia to Des Moines. However, there are services departing from Columbia and arriving at Des Moines via Kansas City Bus Station. The journey, including transfers, takes approximately 6h 8m.
The distance between Columbia and Des Moines is 321 miles. The road distance is 226.5 miles.
The best way to get from Columbia to Des Moines without a car is to bus via Columbia which takes 6h 8m and costs $75 - $130.
It takes approximately 6h 8m to get from Columbia to Des Moines, including transfers.
Columbia to Des Moines bus services, operated by Greyhound USA, depart from Columbia station.
The best way to get from Columbia to Des Moines is to bus via Columbia which takes 6h 8m and costs $75 - $130. Alternatively, you can fly, which costs $180 - $750 and takes 4h 38m.
Columbia to Des Moines bus services, operated by Greyhound USA, arrive at Kansas City Bus Station.
Yes, the driving distance between Columbia to Des Moines is 226 miles. It takes approximately 4h 43m to drive from Columbia to Des Moines.
What companies run services between Columbia, MO, USA and Des Moines, IA, USA?
You can take a vehicle from Columbia to Des Moines via Columbia and Kansas City Bus Station in around 6h 8m. Alternatively, United Airlines and American Airlines fly from Columbia Regional Airport (COU) to Des Moines (DSM) every 3 hours.
- Website
- aa.com
Flights from Columbia Regional Airport to Des Moines via Charlotte
- Ave. Duration
- 5h 39m
- When
- Sunday
- Estimated price
- $210–950
Flights from Columbia Regional Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 6h 31m
- When
- Every day
- Estimated price
- $110–650
Flights from Columbia Regional Airport to Des Moines via Dallas/Ft.Worth
- Ave. Duration
- 6h 45m
- When
- Every day
- Estimated price
- $170–800
- Website
- united.com
Flights from Columbia Regional Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 5h 35m
- When
- Every day
- Estimated price
- $110–650
Flights from Columbia Regional Airport to Des Moines via Denver
- Ave. Duration
- 7h 19m
- When
- Every day
- Estimated price
- $180–850
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Columbia to Kansas City Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Every 4 hours
- Estimated price
- $18–35
- Website
- Greyhound
Bus from Kansas City Bus Station to Des Moines
- Ave. Duration
- 3h 10m
- Frequency
- Twice daily
- Estimated price
- $29–60
- Website
- Greyhound
Bus from Columbia to Kansas City Bus Station
- Ave. Duration
- 2h 45m
- Frequency
- 4 times a day
- Estimated price
- $19–40
- Website
- Greyhound
Bus from Kansas City Bus Station to Des Moines
- Ave. Duration
- 3h 10m
- Frequency
- Twice daily
- Estimated price
- $29–60
- Website
- Greyhound
Bus from Columbia to Kansas City Bus Station
- Ave. Duration
- 2h 45m
- Frequency
- 4 times a day
- Estimated price
- $19–40
- Website
- Greyhound
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Kansas City to Des Moines
- Ave. Duration
- 3h 25m
- Frequency
- 3 times a day
- Estimated price
- $50–75
- Book at
- Jefferson Lines
- Adult
- $50–75
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