There are 5 ways to get from Columbia to Fort Myers by plane, bus (Greyhound, Flixbus), car, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Columbia Regional Airport
best- Fly from Columbia Regional Airport (COU) to Ft. Myers (RSW)plane COU - RSW
7h 46m$178–671Bus to Lambert–St. Louis International Airport, fly
cheapest- Take the bus from Columbia to St Louis Bus Stationbus
- Fly from Lambert–St. Louis International Airport (STL) to Ft. Myers (RSW)plane STL - RSW
9h 46m$159–702Bus
- Take the bus from Columbia to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Tampa Bus Stationbus
- Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus
29h 45m$193–359Drive 1,218.8 mi
- Drive from Columbia to Fort Myerscar 1,218.8 mi
21h 35m$223–322Bus, train
- Take the bus from Columbia to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to New Orleans Bus Stationbus
- Take the train from New Orleans Union Passenger Terminal to Gulfport Amtrak Statrain
- Take the bus from Gulfport to Fort Myersbus
37h 41m$263–439
Columbia to Fort Myers by bus
Questions & Answers
The cheapest way to get from Columbia to Fort Myers is to bus which costs $190 - $360 and takes 29h 45m.
The fastest way to get from Columbia to Fort Myers is to fly which takes 7h 46m and costs $170 - $700.
No, there is no direct bus from Columbia to Fort Myers. However, there are services departing from Columbia and arriving at Fort Myers Bus Stop via St Louis Bus Station, Atlanta Bus Station and Tampa Bus Station. The journey, including transfers, takes approximately 29h 45m.
The distance between Columbia and Fort Myers is 1077 miles. The road distance is 1225.9 miles.
The best way to get from Columbia to Fort Myers without a car is to bus which takes 29h 45m and costs $190 - $360.
It takes approximately 7h 46m to get from Columbia to Fort Myers, including transfers.
Columbia to Fort Myers bus services, operated by Greyhound USA, depart from Columbia station.
The best way to get from Columbia to Fort Myers is to fly which takes 7h 46m and costs $170 - $700. Alternatively, you can bus, which costs $190 - $360 and takes 29h 45m.
Columbia to Fort Myers bus services, operated by Greyhound USA, arrive at St Louis Bus Station.
Fort Myers is 1h ahead of Columbia. It is currently 9:22 AM in Columbia and 10:22 AM in Fort Myers.
What companies run services between Columbia, MO, USA and Fort Myers, FL, USA?
American Airlines and United Airlines fly from Columbia Regional Airport (COU) to Ft. Myers (RSW) every 4 hours. Alternatively, you can take a bus from Columbia to Fort Myers Bus Stop via St Louis Bus Station, Atlanta Bus Station, and Tampa Bus Station in around 29h 45m.
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to Ft. Myers
- Ave. Duration
- 2h 30m
- When
- Every day
- Estimated price
- $130–650
Flights from Lambert–St. Louis International Airport to Ft. Myers via Nashville
- Ave. Duration
- 4h 5m
- When
- Monday, Thursday, Friday, Tuesday, Wednesday, and Sunday
- Estimated price
- $130–650
Flights from Lambert–St. Louis International Airport to Ft. Myers via Orlando
- Ave. Duration
- 4h 56m
- When
- Saturday, Monday, Thursday, Friday, and Sunday
- Estimated price
- $130–650
- Website
- aa.com
Flights from Columbia Regional Airport to Ft. Myers via Dallas/Ft.Worth
- Ave. Duration
- 8h 11m
- When
- Every day
- Estimated price
- $140–650
Flights from Columbia Regional Airport to Ft. Myers via Chicago O'Hare
- Ave. Duration
- 9h 2m
- When
- Every day
- Estimated price
- $130–650
Flights from Columbia Regional Airport to Ft. Myers via Charlotte
- Ave. Duration
- 9h 31m
- When
- Every day
- Estimated price
- $120–600
Flights from Lambert–St. Louis International Airport to Ft. Myers via Charlotte
- Ave. Duration
- 4h 51m
- When
- Every day
- Estimated price
- $140–700
- Website
- delta.com
Flights from Lambert–St. Louis International Airport to Ft. Myers via Atlanta
- Ave. Duration
- 4h 47m
- When
- Every day
- Estimated price
- $130–650
- Website
- united.com
Flights from Columbia Regional Airport to Ft. Myers via Chicago O'Hare
- Ave. Duration
- 8h 1m
- When
- Every day
- Estimated price
- $130–650
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from New Orleans Union Passenger Terminal to Gulfport Amtrak Sta
- Ave. Duration
- 59 min
- Frequency
- Twice daily
- Estimated price
- $20–45
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Columbia to St Louis Bus Station
- Ave. Duration
- 3h 35m
- Frequency
- Twice daily
- Estimated price
- $23–45
- Website
- Greyhound
Bus from St Louis Bus Station to Atlanta Bus Station
- Ave. Duration
- 11h 40m
- Frequency
- Once daily
- Estimated price
- $80–160
- Website
- Greyhound
Bus from Columbia to St Louis Bus Station
- Ave. Duration
- 3h 35m
- Frequency
- Twice daily
- Estimated price
- $23–45
- Website
- Greyhound
Bus from Columbia to St Louis Bus Station
- Ave. Duration
- 3h 35m
- Frequency
- Twice daily
- Estimated price
- $23–45
- Website
- Greyhound
Bus from St Louis Bus Station to New Orleans Bus Station
- Ave. Duration
- 16h 50m
- Frequency
- Once daily
- Estimated price
- $100–200
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from St Louis Bus Station to Atlanta Bus Station
- Ave. Duration
- 10h
- Frequency
- 5 times a week
- Estimated price
- $85–140
- Schedules at
- Flixbus USA
Bus from Atlanta Bus Station to Tampa Bus Station
- Ave. Duration
- 8h 25m
- Frequency
- Once daily
- Estimated price
- $70–120
- Schedules at
- Flixbus USA
Bus from Tampa Bus Station to Fort Myers Bus Stop
- Ave. Duration
- 3h 5m
- Frequency
- 3 times a day
- Estimated price
- $20–35
- Schedules at
- Flixbus USA
- Phone
- +1 800-923-1799
- [email protected]
- Website
- Omnibus Express
Bus from Gulfport to Fort Myers
- Ave. Duration
- 13h 17m
- Frequency
- Once daily
- Estimated price
- $120–150
- Schedules at
- Omnibus Express
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More Questions & Answers
Yes, the driving distance between Columbia to Fort Myers is 1226 miles. It takes approximately 21h 35m to drive from Columbia to Fort Myers.
Book your Columbia to Fort Myers bus tickets online with Omio and FlixBus.
There are 2658+ hotels available in Fort Myers.








