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How to get fromColumbia to Key Westby plane, bus (Greyhound, Flixbus), taxi, train, bus, car, or ferry

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There are 6 ways to get from Columbia to Key West by plane, bus (Greyhound, Flixbus), taxi, train, bus, car, or ferry

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Columbia Regional Airport

    best
    1. Fly from Columbia Regional Airport (COU) to Key West International Airport (EYW)plane plane COU - EYW
    8h 15m
    $166–519

  2. Bus to Lambert–St. Louis International Airport, fly

    cheapest
    1. Take the bus from Columbia to St Louis Bus Stationbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Key West International Airport (EYW)plane plane STL - EYW
    9h 49m
    $148–561

  3. Bus

    1. Take the bus from Columbia to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Miami Airport Stationbus bus
    4. Take the bus from Miami Airport Station to Big Pine Keybus bus
    5. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    37h 41m
    $230–459

  4. Taxi, train, bus

    1. Take the taxi from Columbia to Jefferson City Stationtaxi taxi
    2. Take the train from Jefferson City Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Miami Amtrak Stationtrain train
    4. Take the bus from Miami Airport Station to Big Pine Keybus bus
    5. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    2d 15h
    $943–1,883

  5. Drive 1,462.7 mi

    1. Drive from Columbia to Key Westcar car 1,462.7 mi
    26h 20m
    $267–386

  6. Bus, train, ferry

    1. Take the bus from Columbia to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to New Orleans Bus Stationbus bus
    3. Take the train from New Orleans Union Passenger Terminal to Gulfport Amtrak Statrain train
    4. Take the bus from Gulfport to Fort Myersbus bus
    5. Take the ferry from Fort Myers Beach, FL to Key West, FLferry ferry
    43h 7m
    $445–640

Columbia to Key West by bus and foot

Calendar12Weekly Services
Duration37h 41mAverage Duration
Ticket$230Cheapest Price
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Questions & Answers

Map of how to get from Columbia to Key West.ExpandLaunch map view
  • Distance: 1,175.4 mi
  • Duration: 8h 15m

What companies run services between Columbia, MO, USA and Key West, FL, USA?

United Airlines and American Airlines fly from Columbia Regional Airport (COU) to Key West International Airport (EYW) every 4 hours. Alternatively, you can take a bus from Columbia to N Roosevelt & 3rd Street via St Louis Bus Station, Atlanta Bus Station, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 37h 41m.

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