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How to get fromColumbia to Mobileby plane, bus, train, or car

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There are 7 ways to get from Columbia to Mobile by plane, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Columbia Regional Airport to Mobile Regional Airport

    best
    1. Fly from Columbia Regional Airport (COU) to Mobile Regional Airport (MOB)plane plane COU - MOB
    8h 29m
    $150–516

  2. Bus to Lambert–St. Louis International Airport, fly to Destin–Fort Walton Beach Airport, drive

    cheapest
    1. Take the bus from Columbia to St Louis Bus Stationbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Destin–Fort Walton Beach Airport (VPS)plane plane STL - VPS
    3. Drive from Destin–Fort Walton Beach Airport (VPS) to Mobilecar car
    9h 10m
    $130–545

  3. Bus, train

    1. Take the bus from Columbia to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to New Orleans Bus Stationbus bus
    3. Take the train from New Orleans Union Passenger Terminal to Mobile Amtrak Statrain train
    25h 8m
    $153–334

  4. Bus, train via Carbondale

    1. Take the bus from Columbia to St Louis Bus Stationbus bus
    2. Take the bus from St. Louis to Carbondalebus bus
    3. Take the train from Carbondale to New Orleans Union Passenger Terminaltrain train
    4. Take the train from New Orleans Union Passenger Terminal to Mobile Amtrak Statrain train
    25h 11m
    $258–589

  5. Drive 725.1 mi

    1. Drive from Columbia to Mobilecar car 725.1 mi
    14h 1m
    $133–192

  6. Fly Columbia Regional Airport to Destin–Fort Walton Beach Airport, drive

    1. Fly from Columbia Regional Airport (COU) to Destin–Fort Walton Beach Airport (VPS)plane plane COU - VPS
    2. Drive from Destin–Fort Walton Beach Airport (VPS) to Mobilecar car
    4h 17m
    $144–474

  7. Fly Columbia Regional Airport to Pensacola International Airport, bus

    1. Fly from Columbia Regional Airport (COU) to Pensacola International Airport (PNS)plane plane COU - PNS
    2. Take the bus from Pensacola Airport to Mobile Bus Stationbus bus
    9h 17m
    $154–504

Columbia to Mobile by bus and train

Calendar7Weekly Services
Duration25h 8mAverage Duration
Ticket$153Cheapest Price
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Questions & Answers

Map of how to get from Columbia to Mobile.ExpandLaunch map view
  • Distance: 642.3 mi
  • Duration: 8h 29m

What companies run services between Columbia, MO, USA and Mobile, AL, USA?

American Airlines flies from Columbia Regional Airport (COU) to Mobile Regional Airport (MOB) 3 times a day.

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Train operators
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