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How to get fromColumbia to Myrtle Beachby plane, bus (Greyhound, Flixbus, Amtrak), car, bus, or bus (Greyhound, Flixbus)

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There are 5 ways to get from Columbia to Myrtle Beach by plane, bus (Greyhound, Flixbus, Amtrak), car, bus, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Columbia Regional Airport

    best
    1. Fly from Columbia Regional Airport (COU) to Myrtle Beach (MYR)plane plane COU - MYR
    4h 43m
    $136–440

  2. Bus to Lambert–St. Louis International Airport, fly

    cheapest
    1. Take the bus from Columbia to St Louis Bus Stationbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Myrtle Beach (MYR)plane plane STL - MYR
    7h 19m
    $122–501

  3. Bus via Carbondale

    1. Take the bus from Columbia to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Carbondale Intermodal Stationbus bus
    3. Take the bus from Carbondale Intermodal Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Myrtle Beach Bus Stationbus bus
    25h 10m
    $163–319

  4. Drive 993.6 mi

    1. Drive from Columbia to Myrtle Beachcar car 993.6 mi
    18h 7m
    $182–262

  5. Bus

    1. Take the bus from Columbia to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Myrtle Beach Bus Stationbus bus
    25h 55m
    $163–314

Columbia to Myrtle Beach by bus

Calendar10Weekly Buses
Duration25h 10mAverage Duration
Ticket$163Cheapest Price
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Questions & Answers

Map of how to get from Columbia to Myrtle Beach.ExpandLaunch map view
  • Distance: 836.7 mi
  • Duration: 4h 43m

What companies run services between Columbia, MO, USA and Myrtle Beach, SC, USA?

American Airlines and United Airlines fly from Columbia Regional Airport (COU) to Myrtle Beach (MYR) twice daily. Alternatively, you can take a bus from Columbia to Myrtle Beach Bus Station via St Louis Bus Station, Carbondale Intermodal Station, and Atlanta Bus Station in around 25h 10m.

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