There are 5 ways to get from Columbia to Sikeston by taxi, train, bus, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Taxi, train, bus
best- Take the taxi from Columbia to Jefferson City Stationtaxi
- Take the train from Jefferson City Station to St. Louistrain
- Take the bus from St Louis Bus Station to Cape Girardeaubus
- Take the taxi from Cape Girardeau to Sikestontaxi
6h 47m$265–380Drive 253.1 mi
cheapest- Drive from Columbia to Sikestoncar 253.1 mi
4h 19m$47–67Fly to Barkley Regional Airport, drive
- Fly from Columbia Regional Airport (COU) to Barkley Regional Airport (PAH)plane COU - PAH
- Drive from Barkley Regional Airport (PAH) to Sikestoncar
8h 22m$135–461Bus, taxi
- Take the bus from Columbia to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Cape Girardeaubus
- Take the taxi from Cape Girardeau to Sikestontaxi
7h 15m$130–199Fly to Williamson County Regional Airport, bus
- Fly from Columbia Regional Airport (COU) to Williamson County Regional Airport (MWA)plane COU - MWA
- Take the bus from Marathon Gas Station - Marion to Flying J - Matthewsbus
7h 2m$198–637
Columbia Regional Airport (COU) to Barkley Regional Airport (PAH) flights
Questions & Answers
The cheapest way to get from Columbia to Sikeston is to drive which costs $45 - $70 and takes 4h 19m.
The fastest way to get from Columbia to Sikeston is to drive which takes 4h 19m and costs $45 - $70.
The distance between Columbia and Sikeston is 301 miles. The road distance is 254.5 miles.
The best way to get from Columbia to Sikeston without a car is to taxi and train and bus which takes 6h 47m and costs $260 - $380.
It takes approximately 6h 47m to get from Columbia to Sikeston, including transfers.
Yes, the driving distance between Columbia to Sikeston is 255 miles. It takes approximately 4h 19m to drive from Columbia to Sikeston.
There are 12+ hotels available in Sikeston.
What companies run services between Columbia, MO, USA and Sikeston, MO, USA?
There is no direct connection from Columbia to Sikeston. However, you can take the taxi to Jefferson City Station, take the train to St. Louis, walk to St Louis Bus Station, take the bus to Cape Girardeau, then take the taxi to Sikeston. Alternatively, you can drive from Columbia to Sikeston in around 4h 19m.
- Website
- contouraviation.com
Flights from Columbia Regional Airport to Williamson County Regional Airport via Chicago O'Hare
- Ave. Duration
- 6h 4m
- When
- Every day
- Estimated price
- $65–380
- Website
- united.com
Flights from Columbia Regional Airport to Barkley Regional Airport via Chicago O'Hare
- Ave. Duration
- 7h 2m
- When
- Every day
- Estimated price
- $70–380
- Website
- aa.com
Flights from Columbia Regional Airport to Williamson County Regional Airport via Chicago O'Hare
- Ave. Duration
- 3h 57m
- When
- Every day
- Estimated price
- $65–380
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Jefferson City Station to St. Louis
- Ave. Duration
- 2h 33m
- Frequency
- Twice daily
- Estimated price
- $35–80
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from St Louis Bus Station to Cape Girardeau
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $17–35
- Website
- Greyhound
Bus from Columbia to St Louis Bus Station
- Ave. Duration
- 3h 35m
- Frequency
- Twice daily
- Estimated price
- $23–45
- Website
- Greyhound
Bus from St Louis Bus Station to Cape Girardeau
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $17–35
- Website
- Greyhound
- Phone
- +1 888 358 6762
- [email protected]
- Website
- Tornado Bus Company
Bus from Marathon Gas Station - Marion to Flying J - Matthews
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- $40–140
- Schedules at
- Tornado Bus Company
- Adults 11-59
- $40–140
- Ave. Duration
- 34 min
- Estimated price
- $90–150
Taxi Terry's
- Phone
- +1-573-441-1414
- Website
- taxicolumbiamo.com
Howard's Taxi Full Throttle
- Phone
- +1-573-270-9932
Howard's Taxi Full Throttle
- Phone
- +1-573-270-9932
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