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How to get fromColumbia to Winston-Salemby plane, bus (Greyhound, Amtrak, Flixbus), car, bus, bus (Greyhound, Flixbus), or train

Find Transport to Winston-Salem

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There are 6 ways to get from Columbia to Winston-Salem by plane, bus (Greyhound, Amtrak, Flixbus), car, bus, bus (Greyhound, Flixbus), or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Piedmont Triad International Airport

    best
    1. Fly from Columbia Regional Airport (COU) to Piedmont Triad International Airport (GSO)plane plane COU - GSO
    5h 32m
    $204–789

  2. Bus via Carbondale

    cheapest
    1. Take the bus from Columbia to St Louis Bus Stationbus bus
    2. Take the bus from St. Louis to Carbondalebus bus
    3. Take the bus from Carbondale Intermodal Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Winston Salem(Trans Center)bus bus
    23h
    $147–304

  3. Drive 802.3 mi

    1. Drive from Columbia to Winston-Salemcar car 802.3 mi
    14h 31m
    $147–212

  4. Fly to Charlotte Douglas International Airport, bus

    1. Fly from Columbia Regional Airport (COU) to Charlotte Douglas International Airport (CLT)plane plane COU - CLT
    2. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    5h 45m
    $166–712

  5. Bus

    1. Take the bus from Columbia to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Winston Salem(Trans Center)bus bus
    23h 35m
    $148–299

  6. Bus, train

    1. Take the bus from Columbia to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Indianapolis Union Stationbus bus
    3. Take the train from Indianapolis to Ashland Amtrak Stationtrain train
    4. Take the bus from Ashland Bus Station to Winston Salem(Trans Center)bus bus
    24h 35m
    $183–379

Columbia to Winston-Salem by bus

Calendar5Weekly Buses
Duration23hAverage Duration
Ticket$147Cheapest Price
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Questions & Answers

Map of how to get from Columbia to Winston-Salem.ExpandLaunch map view
  • Distance: 735.3 mi
  • Duration: 5h 32m

What companies run services between Columbia, MO, USA and Winston-Salem, NC, USA?

American Airlines and United Airlines fly from Columbia Regional Airport (COU) to Piedmont Triad International Airport (GSO) every 4 hours. Alternatively, you can take a bus from Columbia to Winston Salem(Trans Center) via St Louis Bus Station, St. Louis, Carbondale Intermodal Station, and Atlanta Bus Station in around 23h.

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