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How to get fromColumbia to Buffaloby car, plane, bus (Flixbus), train, or bus

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There are 5 ways to get from Columbia to Buffalo by car, plane, bus (Flixbus), train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Charleston International Airport, fly

    best
    1. Drive from Columbia to Charleston-Airport-CHScar car
    2. Fly from Charleston International Airport (CHS) to Buffalo Niagara International Airport (BUF)plane plane CHS - BUF
    5h 12m
    $153–804
  2. Fly from Columbia

    cheapest
    1. Fly from Columbia (CAE) to Buffalo Niagara International Airport (BUF)plane plane CAE - BUF
    6h 45m
    $106–630
  3. Bus

    1. Take the bus from Columbia, SC to New York, NYbus bus Augusta
    2. Take the bus from New York Midtown to Buffalobus bus FlixBus 2686 / ...
    26h 41m
    $168–252
  4. Train, bus

    1. Take the train from Columbia Station to Pittsburgh Amtrak Stationtrain train Floridian
    2. Take the bus from Pittsburgh, Pa to Buffalo, Nybus bus 510
    28h 8m
    $483–862
  5. Drive  744.9 mi

    1. Drive from Columbia to Buffalocar car 744.9 mi
    12h 44m
    $128–184

Columbia to Buffalo by train and bus

Calendar7Weekly Services
Duration28h 8mAverage Duration
Ticket$483Cheapest Price
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Comparing Your Travel Options

What companies run services between Columbia, SC, USA and Buffalo, NY, USA?

You can take a bus from Sumter Laurel South to Buffalo via Broad Marley North, Columbia, SC, New York, NY, New York City Chinatown, and New York Midtown in around 26h 41m. Alternatively, United Airlines, Delta, and American Airlines fly from Columbia (CAE) to Buffalo Niagara International Airport (BUF) hourly.

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