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How to get fromColumbia to Chicagoby plane, bus (Greyhound, Flixbus), train (Amtrak), or car

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There are 5 ways to get from Columbia to Chicago by plane, bus (Greyhound, Flixbus), train (Amtrak), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Chicago O'Hare International Airport

    best
    1. Fly from Columbia (CAE) to Chicago O'Hare International Airport (ORD)plane plane CAE - ORD
    4h 37m
    $144–756
  2. Drive 764.1 mi

    cheapest
    1. Drive from Columbia to Chicagocar car 764.1 mi
    14h 10m
    $140–202
  3. Bus

    1. Take the bus from Columbia, SC to Camdenbus bus
    2. Take the bus from Camden to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Chicago Bus Stationbus bus
    23h 34m
    $174–336
  4. Train (Amtrak)

    1. Take the train from Columbia Station to Chicago Union Stationtrain train Floridian
    29h 23m
    $410–850
  5. Fly to Chicago Midway International Airport

    1. Fly from Columbia (CAE) to Chicago Midway International Airport (MDW)plane plane CAE - MDW
    6h 16m
    $164–856

Columbia to Chicago by train (Amtrak)

Calendar7Weekly Trains
Duration29h 23mAverage Duration
Ticket$410Cheapest Price
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Questions & Answers

What companies run services between Columbia, SC, USA and Chicago, IL, USA?

American Airlines, United Airlines, and Delta fly from Columbia (CAE) to Chicago O'Hare International Airport (ORD) hourly. Alternatively, you can take a bus from Sumter Laurel South to Chicago Bus Station via Broad Marley North, Columbia, SC, Camden, and Atlanta Bus Station in around 23h 34m.

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