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How to get fromColumbia to Des Moinesby plane, bus (Greyhound, Flixbus), train, bus, or car

Find Transport to Des Moines

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There are 5 ways to get from Columbia to Des Moines by plane, bus (Greyhound, Flixbus), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Columbia (CAE) to Des Moines (DSM)plane plane CAE - DSM
    5h 58m
    $358–1,722

  2. Drive 1,051.1 mi

    cheapest
    1. Drive from Columbia to Des Moinescar car 1,051.1 mi
    18h 54m
    $192–278

  3. Bus

    1. Take the bus from Columbia, SC to Camdenbus bus
    2. Take the bus from Camden to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    4. Take the bus from St Louis Bus Station to Des Moinesbus bus
    30h 23m
    $210–406

  4. Train, bus

    1. Take the train from Columbia Station to Chicago Union Stationtrain train Floridian
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123S / ...
    37h 2m
    $464–940

  5. Train, bus via Galesburg

    1. Take the train from Columbia Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain train
    3. Take the bus from Galesburg to Des Moinesbus bus
    38h 54m
    $494–1,010

Columbia to Des Moines by train, foot, and bus

Calendar7Weekly Services
Duration37h 2mAverage Duration
Ticket$464Cheapest Price
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Questions & Answers

Map of how to get from Columbia to Des Moines.ExpandLaunch map view
  • Distance: 875.7 mi
  • Duration: 5h 58m

What companies run services between Columbia, SC, USA and Des Moines, IA, USA?

Delta, United Airlines, and American Airlines fly from Columbia (CAE) to Des Moines (DSM) hourly. Alternatively, you can take a bus from Sumter Laurel South to Des Moines via Broad Marley North, Columbia, SC, Camden, Atlanta Bus Station, and St Louis Bus Station in around 30h 23m.

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