There are 6 ways to get from Columbia to Florida Keys by plane, train, shuttle, car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Columbia to Key West International Airport
best- Fly from Columbia (CAE) to Key West International Airport (EYW)plane CAE - EYW
8h 30m$134–396Drive 775.8 mi
cheapest- Drive from Columbia to Florida Keyscar 775.8 mi
13h 25m$133–192Train, shuttle
- Take the train from Columbia Station to Miami Amtrak Stationtrain Floridian
- Take a shuttle bus from Miami, FL - International Airport to Summerland Key - Mote Marine LabTo the Keys
24h 19m$583–849Drive to Charleston International Airport, fly to Miami International Airport, shuttle
- Drive from Columbia to Charleston-Airport-CHScar
- Fly from Charleston International Airport (CHS) to Miami International Airport (MIA)plane CHS - MIA
- Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FL
9h 3m$640–1,210Drive to Charleston International Airport, fly to Fort Lauderdale–Hollywood International Airport, shuttle
- Drive from Columbia to Charleston-Airport-CHScar
- Fly from Charleston International Airport (CHS) to Fort Lauderdale–Hollywood International Airport (FLL)plane CHS - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FL
9h 28m$260–660Bus to Augusta Regional Airport At Bush Field, fly to Key West International Airport
- Take the bus from Columbia, SC to Augustabus
- Fly from Augusta Regional Airport At Bush Field (AGS) to Key West International Airport (EYW)plane AGS - EYW
11h 4m$188–480
Columbia to Florida Keys by train, foot, tram, shuttle, and bus
Comparing Your Travel Options
The cheapest way to get from Columbia to Florida Keys is to drive which costs $130 - $200 and takes 13h 25m.
The fastest way to get from Columbia to Florida Keys is to fly which takes 8h 30m and costs $130 - $400.
The distance between Columbia and Florida Keys is 684 miles. The road distance is 780.3 miles.
The best way to get from Columbia to Florida Keys without a car is to train and shuttle which takes 24h 19m and costs $550 - $850.
It takes approximately 8h 30m to get from Columbia to Florida Keys, including transfers.
Yes, the driving distance between Columbia to Florida Keys is 780 miles. It takes approximately 13h 25m to drive from Columbia to Florida Keys.
There are 958+ hotels available in Florida Keys.
What companies run services between Columbia, SC, USA and Florida Keys, FL, USA?
Delta and American Airlines fly from Columbia (CAE) to Key West International Airport (EYW) every 3 hours.
- Website
- aa.com
Flights from Columbia to Key West International Airport via Charlotte
- Ave. Duration
- 5h 41m
- When
- Every day
- Estimated price
- $60–320
Flights from Columbia to Key West International Airport via Reagan Washington
- Ave. Duration
- 6h 2m
- When
- Every day
- Estimated price
- $85–400
Flights from Columbia to Key West International Airport via Miami International Airport
- Ave. Duration
- 6h 12m
- When
- Saturday
- Estimated price
- $55–300
Flights from Columbia to Key West International Airport via New York La Guardia
- Ave. Duration
- 7h 15m
- When
- Monday to Friday
- Estimated price
- $100–460
Flights from Charleston International Airport to Miami International Airport
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- $55–340
Flights from Charleston International Airport to Miami International Airport via Charlotte
- Ave. Duration
- 4h 15m
- When
- Thursday to Saturday
- Estimated price
- $75–390
Flights from Augusta Regional Airport At Bush Field to Key West International Airport via Miami International Airport
- Ave. Duration
- 4h 39m
- When
- Sunday
- Estimated price
- $50–300
Flights from Augusta Regional Airport At Bush Field to Key West International Airport via Charlotte
- Ave. Duration
- 5h 36m
- When
- Every day
- Estimated price
- $60–330
Flights from Augusta Regional Airport At Bush Field to Key West International Airport via Reagan Washington
- Ave. Duration
- 6h 6m
- When
- Monday to Friday
- Estimated price
- $90–410
- Website
- delta.com
Flights from Columbia to Key West International Airport via Atlanta
- Ave. Duration
- 5h 10m
- When
- Every day
- Estimated price
- $60–320
Flights from Charleston International Airport to Miami International Airport via Atlanta
- Ave. Duration
- 4h 22m
- When
- Every day
- Estimated price
- $75–400
Flights from Charleston International Airport to Fort Lauderdale–Hollywood International Airport via Atlanta
- Ave. Duration
- 4h 6m
- When
- Every day
- Estimated price
- $95–550
Flights from Augusta Regional Airport At Bush Field to Key West International Airport via Atlanta
- Ave. Duration
- 5h 7m
- When
- Every day
- Estimated price
- $60–320
- Website
- flybreeze.com
Flights from Charleston International Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 1h 38m
- When
- Monday, Friday, Wednesday, Thursday, Saturday, and Sunday
- Estimated price
- $160–1,000
- Website
- jetblue.com
Flights from Charleston International Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 1h 39m
- When
- Every day
- Estimated price
- $70–430
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Columbia Station to Miami Amtrak Station
- Ave. Duration
- 17h 34m
- Frequency
- Once daily
- Estimated price
- $430–700
- Website
- Amtrak
- Phone
- +1 (305) 289-9997
- [email protected]
- Website
- Keys Shuttle
Shuttle from Miami, FL - International Airport to Summerland Key - Mote Marine Lab
- Ave. Duration
- 3h 30m
- Frequency
- 3 times a day
- Estimated price
- $150–180
- Website
- Keys Shuttle
Shuttle from Miami, FL - International Airport to Big Pine Key, FL
- Ave. Duration
- 3h
- Frequency
- 3 times a day
- Estimated price
- $150–180
- Website
- Keys Shuttle
Shuttle from Fort Lauderdale, FL - International Airport to Big Pine Key, FL
- Ave. Duration
- 3h 30m
- Frequency
- 3 times a day
- Estimated price
- $170–200
- Website
- Keys Shuttle
- Phone
- +1 646-630-7186
- [email protected]
- Website
- Wanda Coach
Bus from Columbia, SC to Augusta
- Ave. Duration
- 1h 34m
- Frequency
- Once daily
- Estimated price
- $30–45
- Website
- Wanda Coach
- Book at
- GotoBus.com
- Adult One Way
- $30–45
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