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How to get fromColumbia to Fort Myersby plane, train, bus, car, or bus (Greyhound, Flixbus)

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There are 5 ways to get from Columbia to Fort Myers by plane, train, bus, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Columbia (CAE) to Ft. Myers (RSW)plane plane CAE - RSW
    7h 23m
    $194–1,006

  2. Bus

    cheapest
    1. Take the bus from Assembly & Gervais South to James E Clyburn Intermodal Transportation Centerbus bus 44
    2. Take the bus from Sumter Bus Stop to Jacksonvillebus bus
    3. Take the bus from Jacksonville to Orlando Bus Stationbus bus
    4. Take the bus from Orlando Bus Station to Fort Myers Bus Stopbus bus
    18h 34m
    $98–192

  3. Train, bus

    1. Take the train from Columbia Station to Tampatrain train Floridian
    2. Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus bus FlixBus 2421
    16h 13m
    $192–383

  4. Train, bus via Jacksonville

    1. Take the train from Columbia Station to Jacksonvilletrain train
    2. Take the bus from Jacksonville to Wildwood Amtrak Stationbus bus
    3. Take the bus from Wildwood to Fort Myersbus bus
    16h 21m
    $196–332

  5. Drive 579.8 mi

    1. Drive from Columbia to Fort Myerscar car 579.8 mi
    10h 9m
    $106–153

Columbia to Fort Myers by train and bus

Calendar7Weekly Services
Duration16h 13mAverage Duration
Ticket$192Cheapest Price
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Questions & Answers

Map of how to get from Columbia to Fort Myers.ExpandLaunch map view
  • Distance: 537.4 mi
  • Duration: 7h 23m

What companies run services between Columbia, SC, USA and Fort Myers, FL, USA?

American Airlines, Delta, and United Airlines fly from Columbia (CAE) to Ft. Myers (RSW) hourly. Alternatively, you can take a bus from Assembly & Gervais South to Fort Myers Bus Stop via James E Clyburn Intermodal Transportation Center, Sumter Bus Stop, Jacksonville, and Orlando Bus Station in around 18h 34m.

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