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How to get fromColumbia to Indianaby plane, train, bus (Greyhound, Flixbus), train (Amtrak), car, or bus

Find Transport to Indiana

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There are 5 ways to get from Columbia to Indiana by plane, train, bus (Greyhound, Flixbus), train (Amtrak), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly, train

    best
    1. Fly from Columbia (CAE) to Chicago O'Hare International Airport (ORD)plane plane CAE - ORD
    2. Take the train from Van Buren St. to Gary Metro Centertrain train
    5h 46m
    $66–316

  2. Bus

    1. Take the bus from Columbia, SC to Camdenbus bus
    2. Take the bus from Camden to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Indianapolisbus bus
    20h 53m
    $164–252

  3. Train (Amtrak)

    1. Take the train from Columbia Station to Alexandriatrain train Floridian
    2. Take the train from Alexandria to Indianapolistrain train Cardinal
    29h 17m
    $663–1,019

  4. Drive  584.6 mi

    1. Drive from Columbia to Indianapoliscar car 584.6 mi
    10h 59m
    $107–155

  5. Train, bus

    1. Take the train from Columbia Station to Toledotrain train Floridian
    2. Take the bus from Toledo to Indianapolisbus bus Bsb 15
    29h 51m
    $594–944

Columbia to Indiana by train (Amtrak)

Calendar3Weekly Trains
Duration29h 17mAverage Duration
Ticket$663Cheapest Price
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Comparing Your Travel Options

Map of how to get from Columbia to Indiana.ExpandLaunch map view
  • Distance: 722.6 mi
  • Duration: 5h 46m

What companies run services between Columbia, SC, USA and Indiana, USA?

You can take a bus from Sumter Laurel South to Indianapolis via Broad Marley North, Columbia, SC, Camden, and Atlanta Bus Station in around 20h 53m. Alternatively, you can take a train from Columbia Station to Indianapolis via Alexandria in around 29h 17m.

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