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How to get fromColumbia to Indianapolisby plane, bus (Greyhound, Flixbus), train (Amtrak), car, train, or bus

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There are 5 ways to get from Columbia to Indianapolis by plane, bus (Greyhound, Flixbus), train (Amtrak), car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Columbia (CAE) to Indianapolis (IND)plane plane CAE - IND
    5h 57m
    $214–1,204

  2. Drive 584.6 mi

    cheapest
    1. Drive from Columbia to Indianapoliscar car 584.6 mi
    10h 59m
    $107–155

  3. Bus

    1. Take the bus from Columbia, SC to Camdenbus bus
    2. Take the bus from Camden to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Indianapolisbus bus
    20h 53m
    $154–276

  4. Train (Amtrak)

    1. Take the train from Columbia Station to Alexandriatrain train Floridian
    2. Take the train from Alexandria to Indianapolistrain train Cardinal
    29h 17m
    $392–797

  5. Train, bus

    1. Take the train from Columbia Station to Toledotrain train Floridian
    2. Take the bus from Toledo to Indianapolis, INbus bus Detroit
    29h 51m
    $361–751

Columbia to Indianapolis by train (Amtrak)

Calendar3Weekly Trains
Duration29h 17mAverage Duration
Ticket$392Cheapest Price
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Questions & Answers

Map of how to get from Columbia to Indianapolis.ExpandLaunch map view
  • Distance: 514 mi
  • Duration: 5h 57m

What companies run services between Columbia, SC, USA and Indianapolis, IN, USA?

Delta, American Airlines, and United Airlines fly from Columbia (CAE) to Indianapolis (IND) hourly. Alternatively, you can take a bus from Sumter Laurel South to Indianapolis via Broad Marley North, Columbia, SC, Camden, and Atlanta Bus Station in around 20h 53m.

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