Rome2Rio

How to get fromColumbia to Key Largoby car, plane, shuttle, train, bus, or bus (Greyhound, Flixbus)

Find Transport to Key Largo

See all options

There are 7 ways to get from Columbia to Key Largo by car, plane, shuttle, train, bus, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Charleston International Airport, fly to Miami International Airport, shuttle

    best
    1. Drive from Columbia to Charleston-Airport-CHScar car
    2. Fly from Charleston International Airport (CHS) to Miami International Airport (MIA)plane plane CHS - MIA
    3. Take a shuttle bus from Miami, FL - International Airport to Key Largo, FLshuttle bus
    5h 48m
    $588–1,156

  2. Drive  694.1 mi

    cheapest
    1. Drive from Columbia to Key Largocar car 694.1 mi
    11h 32m
    $119–172

  3. Train, bus

    1. Take the train from Columbia Station to Miami Amtrak Stationtrain train Floridian
    2. Take the bus from W Palm Dr @ 3 Ave to Mile Marker 98 Key Largobus bus 301
    21h 21m
    $436–665

  4. Bus

    1. Take the bus from Assembly & Gervais South to James E Clyburn Intermodal Transportation Centerbus bus 44
    2. Take the bus from Sumter Bus Stop to Jacksonvillebus bus
    3. Take the bus from Jacksonville to Miami Airport Stationbus bus
    4. Take the bus from Miami Airport Station to Key Largo Bus Stopbus bus
    22h 6m
    $132–222

  5. Drive to Greenville–Spartanburg International Airport, fly to Miami International Airport, shuttle

    1. Drive from Columbia to Greenville–Spartanburg International Airport (GSP)car car
    2. Fly from Greenville–Spartanburg International Airport (GSP) to Miami International Airport (MIA)plane plane GSP - MIA
    3. Take a shuttle bus from Miami, FL - International Airport to Key Largo, FLshuttle bus
    6h 1m
    $177–495

  6. Drive to Charleston International Airport, fly to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Drive from Columbia to Charleston-Airport-CHScar car
    2. Fly from Charleston International Airport (CHS) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane CHS - FLL
    3. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FLshuttle bus
    6h 13m
    $208–586

  7. Train to Savannah, fly to Miami International Airport, shuttle

    1. Take the train from Columbia Station to Savannah Stationtrain train
    2. Fly from Savannah (SAV) to Miami International Airport (MIA)plane plane SAV - MIA
    3. Take a shuttle bus from Miami, FL - International Airport to Key Largo, FLshuttle bus
    7h 49m
    $276–676

Columbia to Key Largo by train, foot, and bus

Calendar7Weekly Services
Duration21h 21mAverage Duration
Ticket$436Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Columbia to Key Largo.ExpandLaunch map view
  • Distance: 654.3 mi
  • Duration: 5h 48m

What companies run services between Columbia, SC, USA and Key Largo, FL, USA?

You can take a bus from Assembly & Gervais South to Key Largo Bus Stop via James E Clyburn Intermodal Transportation Center, Sumter Bus Stop, Jacksonville, and Miami Airport Station in around 22h 6m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound