There are 5 ways to get from Columbia to Key West by plane, train, shuttle, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Columbia
best- Fly from Columbia (CAE) to Key West International Airport (EYW)plane CAE - EYW
5h 39m$62–304Train, shuttle
- Take the train from Columbia Station to Miami Amtrak Stationtrain Floridian
- Take a shuttle bus from Miami, FL - International Airport to Key West, FLTo the Keys
24h 43m$600–865Drive 791.2 mi
- Drive from Columbia to Key Westcar 791.2 mi
13h 48m$136–196Drive to Charleston International Airport, fly
- Drive from Columbia to Charleston-Airport-CHScar
- Fly from Charleston International Airport (CHS) to Key West International Airport (EYW)plane CHS - EYW
5h 36m$84–349Drive to Greenville–Spartanburg International Airport, fly
- Drive from Columbia to Greenville–Spartanburg International Airport (GSP)car
- Fly from Greenville–Spartanburg International Airport (GSP) to Key West International Airport (EYW)plane GSP - EYW
5h 37m$78–328
Columbia to Key West by train, foot, tram, shuttle, and bus
Comparing Your Travel Options
The cheapest way to get from Columbia to Key West is to fly which costs $60 - $310 and takes 5h 39m.
The fastest way to get from Columbia to Key West is to drive and fly which takes 5h 36m and costs $80 - $350.
The distance between Columbia and Key West is 665 miles. The road distance is 795.8 miles.
The best way to get from Columbia to Key West without a car is to train and shuttle which takes 24h 43m and costs $600 - $900.
It takes approximately 5h 39m to get from Columbia to Key West, including transfers.
Yes, the driving distance between Columbia to Key West is 796 miles. It takes approximately 13h 48m to drive from Columbia to Key West.
There are 958+ hotels available in Key West.
What companies run services between Columbia, SC, USA and Key West, FL, USA?
Delta and American Airlines fly from Columbia (CAE) to Key West International Airport (EYW) every 3 hours.
- Website
- aa.com
Flights from Columbia to Key West International Airport via Charlotte
- Ave. Duration
- 5h 41m
- When
- Every day
- Estimated price
- $55–300
Flights from Columbia to Key West International Airport via Reagan Washington
- Ave. Duration
- 6h 2m
- When
- Every day
- Estimated price
- $80–380
Flights from Columbia to Key West International Airport via Miami
- Ave. Duration
- 6h 12m
- When
- Saturday
- Estimated price
- $50–290
Flights from Columbia to Key West International Airport via New York La Guardia
- Ave. Duration
- 7h 15m
- When
- Monday to Friday
- Estimated price
- $100–430
Flights from Charleston International Airport to Key West International Airport via Miami
- Ave. Duration
- 4h 6m
- When
- Every day
- Estimated price
- $55–310
Flights from Charleston International Airport to Key West International Airport via Charlotte
- Ave. Duration
- 4h 42m
- When
- Every day
- Estimated price
- $70–350
Flights from Greenville–Spartanburg International Airport to Key West International Airport via Miami
- Ave. Duration
- 4h 25m
- When
- Monday, Tuesday, Wednesday, Thursday, and Saturday
- Estimated price
- $55–300
Flights from Greenville–Spartanburg International Airport to Key West International Airport via Charlotte
- Ave. Duration
- 5h 51m
- When
- Every day
- Estimated price
- $55–300
- Website
- delta.com
Flights from Columbia to Key West International Airport via Atlanta
- Ave. Duration
- 5h 7m
- When
- Every day
- Estimated price
- $55–310
Flights from Charleston International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 4h 56m
- When
- Every day
- Estimated price
- $70–350
Flights from Greenville–Spartanburg International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 4h 55m
- When
- Every day
- Estimated price
- $55–300
- Website
- flybreeze.com
Flights from Charleston International Airport to Key West International Airport via Tampa
- Ave. Duration
- 6h 36m
- When
- Tuesday
- Estimated price
- $120–700
- Website
- allegiantair.com
Flights from Greenville–Spartanburg International Airport to Key West International Airport via Orlando Sanford
- Ave. Duration
- 3h 38m
- When
- Sunday
- Estimated price
- $50–290
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Columbia Station to Miami Amtrak Station
- Ave. Duration
- 17h 34m
- Frequency
- Once daily
- Estimated price
- $420–700
- Website
- Amtrak
- Phone
- +1 (305) 289-9997
- [email protected]
- Website
- Keys Shuttle
Shuttle from Miami, FL - International Airport to Key West, FL
- Ave. Duration
- 4h
- Frequency
- 3 times a day
- Estimated price
- $170–200
- Website
- Keys Shuttle
Want to know more about travelling around United States
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