Rome2Rio

How to get fromColumbia to Key West (Island)by plane, train, bus, bus (Greyhound, Flixbus), or car

Find Transport to Key West (Island)

See all options

There are 4 ways to get from Columbia to Key West (Island) by plane, train, bus, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Columbia (CAE) to Key West International Airport (EYW)plane plane CAE - EYW
    5h 26m
    $142–752
  2. Bus

    cheapest
    1. Take the bus from Assembly & Gervais South to James E Clyburn Intermodal Transportation Centerbus bus 44
    2. Take the bus from Sumter Bus Stop to Jacksonvillebus bus
    3. Take the bus from Jacksonville to Miami Airport Stationbus bus
    4. Take the bus from Miami Airport Station to Key West Airportbus bus
    24h 14m
    $124–246
  3. Train, bus

    1. Take the train from Columbia Station to Hollywood Amtrak Stationtrain train Floridian
    2. Take the bus from Miami Airport Station to Key West Airportbus bus Greyhound US0720s
    23h 48m
    $273–554
  4. Drive 791.2 mi

    1. Drive from Columbia to Key Westcar car 791.2 mi
    13h 48m
    $145–209

Columbia to Key West (Island) by train and bus

Calendar7Weekly Services
Duration23h 48mAverage Duration
Ticket$273Cheapest Price
See schedules

Questions & Answers

What companies run services between Columbia, SC, USA and Key West (Island), FL, USA?

Delta and American Airlines fly from Columbia (CAE) to Key West International Airport (EYW) every 4 hours. Alternatively, you can take a bus from Assembly & Gervais South to Key West Airport via James E Clyburn Intermodal Transportation Center, Sumter Bus Stop, Jacksonville, and Miami Airport Station in around 24h 14m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers