There are 4 ways to get from Columbia to Key West (Island) by plane, train, bus, bus (Greyhound, Flixbus), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Columbia (CAE) to Key West International Airport (EYW)plane CAE - EYW
5h 26m$142–752Bus
cheapest- Take the bus from Assembly & Gervais South to James E Clyburn Intermodal Transportation Centerbus 44
- Take the bus from Sumter Bus Stop to Jacksonvillebus
- Take the bus from Jacksonville to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Key West Airportbus
24h 14m$124–246Train, bus
- Take the train from Columbia Station to Hollywood Amtrak Stationtrain Floridian
- Take the bus from Miami Airport Station to Key West Airportbus Greyhound US0720s
23h 48m$273–554Drive 791.2 mi
- Drive from Columbia to Key Westcar 791.2 mi
13h 48m$145–209
Columbia to Key West (Island) by train and bus
Questions & Answers
The cheapest way to get from Columbia to Key West (Island) is to bus which costs $120 - $250 and takes 24h 14m.
The fastest way to get from Columbia to Key West (Island) is to fly which takes 5h 26m and costs $140 - $750.
No, there is no direct bus from Columbia to Key West (Island). However, there are services departing from Assembly & Gervais South and arriving at Key West Airport via Sumter Bus Stop, Jacksonville and Miami Airport Station. The journey, including transfers, takes approximately 24h 14m.
The distance between Columbia and Key West (Island) is 663 miles. The road distance is 795.8 miles.
The best way to get from Columbia to Key West (Island) without a car is to train and bus which takes 23h 48m and costs $270 - $600.
It takes approximately 5h 26m to get from Columbia to Key West (Island), including transfers.
Columbia to Key West (Island) bus services, operated by The COMET, depart from Assembly & Gervais South station.
The best way to get from Columbia to Key West (Island) is to fly which takes 5h 26m and costs $140 - $750. Alternatively, you can bus, which costs $120 - $250 and takes 24h 14m.
Columbia to Key West (Island) bus services, operated by The COMET, arrive at James E Clyburn Intermodal Transportation Center station.
Yes, the driving distance between Columbia to Key West (Island) is 796 miles. It takes approximately 13h 48m to drive from Columbia to Key West (Island).
What companies run services between Columbia, SC, USA and Key West (Island), FL, USA?
Delta and American Airlines fly from Columbia (CAE) to Key West International Airport (EYW) every 4 hours. Alternatively, you can take a bus from Assembly & Gervais South to Key West Airport via James E Clyburn Intermodal Transportation Center, Sumter Bus Stop, Jacksonville, and Miami Airport Station in around 24h 14m.
- Website
- aa.com
Flights from Columbia to Key West International Airport via Miami
- Ave. Duration
- 4h 13m
- When
- Saturday
- Estimated price
- $140–750
Flights from Columbia to Key West International Airport via Charlotte
- Ave. Duration
- 5h 8m
- When
- Every day
- Estimated price
- $160–800
Flights from Columbia to Key West International Airport via Reagan Washington
- Ave. Duration
- 6h 1m
- When
- Saturday
- Estimated price
- $240–1,100
Flights from Columbia to Key West International Airport via New York La Guardia
- Ave. Duration
- 8h 2m
- When
- Every day
- Estimated price
- $290–1,200
- Website
- delta.com
Flights from Columbia to Key West International Airport via Atlanta
- Ave. Duration
- 4h 29m
- When
- Every day
- Estimated price
- $160–800
Flights from Columbia to Key West International Airport via New York La Guardia
- Ave. Duration
- 6h 37m
- When
- Every day
- Estimated price
- $290–1,200
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Columbia Station to Hollywood Amtrak Station
- Ave. Duration
- 17h 11m
- Frequency
- Once daily
- Estimated price
- $240–550
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Miami Airport Station to Key West Airport
- Ave. Duration
- 4h 30m
- Frequency
- 3 times a day
- Estimated price
- $23–45
- Website
- https://www.greyhound.com/
Bus from Sumter Bus Stop to Jacksonville
- Ave. Duration
- 6h 25m
- Frequency
- Once daily
- Estimated price
- $45–90
- Website
- https://www.greyhound.com/
Bus from Jacksonville to Miami Airport Station
- Ave. Duration
- 10h 20m
- Frequency
- Once daily
- Estimated price
- $55–110
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Key West Airport
- Ave. Duration
- 4h 30m
- Frequency
- 3 times a day
- Estimated price
- $23–45
- Website
- https://www.greyhound.com/
- Phone
- +1 803-255-7100
- Website
- catchthecometsc.gov
Bus from Assembly & Gervais South to James E Clyburn Intermodal Transportation Center
- Ave. Duration
- 1h 24m
- Frequency
- Once daily
- Estimated price
- $2
- Schedules at
- catchthecometsc.gov
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Jacksonville to Miami Airport Station
- Ave. Duration
- 8h 55m
- Frequency
- Once daily
- Estimated price
- $60–110
- Schedules at
- flixbus.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
More Questions & Answers
There are 979+ hotels available in Key West (Island).








