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How to get fromColumbia to Kirksvilleby plane, bus, train, train (Amtrak), car, or shuttle

Find Transport to Kirksville

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There are 6 ways to get from Columbia to Kirksville by plane, bus, train, train (Amtrak), car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Columbia to Kirksville Regional Airport

    best
    1. Fly from Columbia (CAE) to Kirksville Regional Airport (IRK)plane plane CAE - IRK
    8h 25m
    $126–496

  2. Bus, train

    1. Take the bus from Columbia, SC to Camdenbus bus
    2. Take the bus from Camden to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Indianapolis Union Stationbus bus
    4. Take the bus from Indianapolis Union Station to Galesburgbus bus
    5. Take the train from Galesburg Amtrak Station to La Plata Stationtrain train
    30h 28m
    $264–496

  3. Train (Amtrak)

    1. Take the train from Columbia Station to Chicago Union Stationtrain train Floridian
    2. Take the train from Chicago Union Station to La Plata Stationtrain train Southwest Chief
    35h 32m
    $535–1,090

  4. Drive 947.9 mi

    1. Drive from Columbia to Kirksvillecar car 947.9 mi
    16h 13m
    $173–250

  5. Bus, bus to Charlotte Douglas International Airport, fly to Columbia Regional Airport, shuttle

    1. Take the bus from Columbia, SC to Camdenbus bus
    2. Take the bus from Camden to Charlotte Bus Stationbus bus
    3. Fly from Charlotte Douglas International Airport (CLT) to Columbia Regional Airport (COU)plane plane CLT - COU
    4. Take a shuttle bus from Columbia to Hy-Vee - Kirksvilleshuttle bus
    11h 33m
    $188–622

  6. Bus, bus to Charlotte Douglas International Airport, fly to The Eastern Iowa Airport, drive

    1. Take the bus from Columbia, SC to Camdenbus bus
    2. Take the bus from Camden to Charlotte Bus Stationbus bus
    3. Fly from Charlotte Douglas International Airport (CLT) to The Eastern Iowa Airport (CID)plane plane CLT - CID
    4. Drive from Cedar-Rapids-Airport-CID to Kirksvillecar car
    12h 16m
    $168–616

Columbia (CAE) to Kirksville Regional Airport (IRK) flights

Calendar22Weekly Planes
Duration9h 19mAverage Duration
Ticket$92Cheapest Price
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Questions & Answers

Map of how to get from Columbia to Kirksville.ExpandLaunch map view
  • Distance: 775.3 mi
  • Duration: 8h 25m

What companies run services between Columbia, SC, USA and Kirksville, MO, USA?

United Airlines, Corporate Flight Management Inc, and two other airlines fly from Columbia (CAE) to Kirksville Regional Airport (IRK) 3 times a day. Alternatively, you can take a train from Columbia Station to Kirksville via Chicago Union Station and La Plata Station in around 35h 32m.

Airlines
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