What is the cheapest way to get from Columbia to Knoxville?

The cheapest way to get from Columbia to Knoxville is to drive which costs $45 - $70 and takes 4h 34m.

What is the fastest way to get from Columbia to Knoxville?

The fastest way to get from Columbia to Knoxville is to drive which takes 4h 34m and costs $45 - $70.

How far is it from Columbia to Knoxville?

The distance between Columbia and Knoxville is 230 miles. The road distance is 264.8 miles.

How long does it take to get from Columbia to Knoxville?

It takes approximately 4h 45m to get from Columbia to Knoxville, including transfers.

Can I drive from Columbia to Knoxville?

Yes, the driving distance between Columbia to Knoxville is 265 miles. It takes approximately 4h 34m to drive from Columbia to Knoxville.

Where can I stay near Knoxville?

There are 320+ hotels available in Knoxville.

Columbia to Knoxville - 3 ways to travel via plane, bus, taxi, shuttle, and car

How to get fromColumbia to Knoxville

Travel from

See all options

Search accommodation with Expedia

There are 3 ways to get from Columbia to Knoxville by plane, bus, taxi, shuttle, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Fly
best
1. Fly from Columbia (CAE) to Mcghee Tyson Airport (TYS)plane CAE - TYS
4h 45m
$236–1,372
Drive 263.3 mi
cheapest
1. Drive from Columbia to Knoxvillecar 263.3 mi
4h 34m
$48–70
Bus, taxi, shuttle, drive
1. Take the bus from Assembly & Gervais South to James E Clyburn Intermodal Transportation Centerbus 44
2. Take the bus from Sumter Bus Stop to Charlotte Bus Stationbus
3. Take the bus from Charlotte Airport to ASU Peacock Hall Boonebus
4. Take the taxi from ASU Peacock Hall Boone to Black Bear Resorttaxi
5. Take a shuttle bus from Black Bear Resort to Hot Springsshuttle
6. Drive from Hot Springs to Chilhowee at Holstoncar
13h 58m
$408–488

Columbia (CAE) to Mcghee Tyson Airport (TYS) flights

139Weekly Planes

4h 34mAverage Duration

$188Cheapest Price

See schedules

Questions & Answers

Map of how to get from Columbia to Knoxville.

Launch map view

Distance: 228.7 mi
Duration: 4h 45m

What companies run services between Columbia, SC, USA and Knoxville, TN, USA?

Delta, American Airlines, and United Airlines fly from Columbia (CAE) to Mcghee Tyson Airport (TYS) hourly.

Airlines

Bus operators

Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Travelling to the US: What do I need to know?

Rome2Rio’s travel guides to the US tell you the best ways to explore the country, from Amtrak to Greyhound to the New York Subway.

Read the travel guide Travelling to the US: What do I need to know?

Need to know: Greyhound

Rome2Rio’s guide on the bus operator has all the information you need

Read the travel guide Need to know: Greyhound

How to get fromColumbia to Knoxvilleby plane, bus, taxi, shuttle, or car

There are 3 ways to get from Columbia to Knoxville by plane, bus, taxi, shuttle, or car

Fly

Drive 263.3 mi

Bus, taxi, shuttle, drive