There are 9 ways to get from Columbia to Mobile by plane, bus (Greyhound), train (Amtrak), car, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Mobile Regional Airport
best- Fly from Columbia (CAE) to Mobile Regional Airport (MOB)plane CAE - MOB
7h 47m$142–802Drive 533.2 mi
cheapest- Drive from Columbia to Mobilecar 533.2 mi
8h 44m$98–141Bus via Sumter
- Take the bus from Assembly & Gervais South to James E Clyburn Intermodal Transportation Centerbus 44
- Take the bus from Sumter to Atlantabus
- Take the bus from Atlanta Bus Station to Mobile Bus Stationbus
16h 23mTrain (Amtrak)
- Take the train from Columbia Station to Carytrain
- Take the train from Cary to Greensborotrain
- Take the train from Greensboro to New Orleans Union Passenger Terminaltrain
- Take the train from New Orleans Union Passenger Terminal to Mobile Amtrak Statrain
32h 46m$397–867Fly to Gulfport-Biloxi Regional Airport, bus
- Fly from Columbia (CAE) to Gulfport-Biloxi Regional Airport (GPT)plane CAE - GPT
- Take the bus from Gulfport to Mobilebus
7h 13m$234–1,032Fly to Pensacola International Airport, bus
- Fly from Columbia (CAE) to Pensacola International Airport (PNS)plane CAE - PNS
- Take the bus from Pensacola Airport to Mobile Bus Stationbus
8h 46m$130–720Bus
- Take the bus from Columbia, SC to Camdenbus
- Take the bus from Camden to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Mobile Bus Stationbus
16h 32m$114–216Bus #2
- Take the bus from Columbia, SC to Camdenbus
- Take the bus from Camden to Atlanta Bus Stationbus
- Take the bus from Atlanta to Grand Baybus
- Take the bus from Grand Bay to Mobilebus
16h 34m$178–270Train, bus
- Take the train from Columbia Station to Jacksonvilletrain Floridian
- Take the bus from Jacksonville to Mobile Bus Stationbus Greyhound US0760S
20h 45m$159–318
Columbia (CAE) to Mobile Regional Airport (MOB) flights
Questions & Answers
The cheapest way to get from Columbia to Mobile is to drive which costs $95 - $150 and takes 8h 44m.
The fastest way to get from Columbia to Mobile is to fly and bus which takes 7h 13m and costs $230 - $1,100.
No, there is no direct bus from Columbia to Mobile. However, there are services departing from Assembly & Gervais South and arriving at Water NB at St Louis St via Sumter, Atlanta Bus Station and Govt EB at Greyhound Bus Station. The journey, including transfers, takes approximately 16h 23m.
No, there is no direct train from Columbia station to Mobile. However, there are services departing from Columbia Station and arriving at Mobile Amtrak Sta via Cary, Greensboro and New Orleans Union Passenger Terminal. The journey, including transfers, takes approximately 32h 46m.
The distance between Columbia and Mobile is 508 miles. The road distance is 536.4 miles.
The best way to get from Columbia to Mobile without a car is to bus via Sumter which takes 16h 23m and costs .
It takes approximately 7h 47m to get from Columbia to Mobile, including transfers.
Columbia to Mobile bus services, operated by The COMET, depart from Assembly & Gervais South station.
Columbia to Mobile train services, operated by Amtrak, depart from Columbia Station.
The best way to get from Columbia to Mobile is to fly which takes 7h 47m and costs $140 - $800. Alternatively, you can bus via Sumter, which costs and takes 16h 23m, you could also train, which costs $390 - $900 and takes 32h 46m.
What companies run services between Columbia, SC, USA and Mobile, AL, USA?
Delta, American Airlines, and United Airlines fly from Columbia (CAE) to Mobile Regional Airport (MOB) every 4 hours. Alternatively, you can take a bus from Assembly & Gervais South to Water NB at St Louis St via James E Clyburn Intermodal Transportation Center, Sumter, Atlanta Bus Station, Mobile Bus Station, and Govt EB at Greyhound Bus Station in around 16h 23m.
- Website
- delta.com
Flights from Columbia to Mobile Regional Airport via Atlanta
- Ave. Duration
- 4h 17m
- When
- Every day
- Estimated price
- $140–800
Flights from Columbia to Gulfport-Biloxi Regional Airport via Atlanta
- Ave. Duration
- 3h 51m
- When
- Every day
- Estimated price
- $170–950
Flights from Columbia to Pensacola International Airport via Atlanta
- Ave. Duration
- 4h 2m
- When
- Every day
- Estimated price
- $120–700
- Website
- aa.com
Flights from Columbia to Mobile Regional Airport via Charlotte
- Ave. Duration
- 5h 9m
- When
- Every day
- Estimated price
- $160–850
Flights from Columbia to Gulfport-Biloxi Regional Airport via Charlotte
- Ave. Duration
- 5h 5m
- When
- Every day
- Estimated price
- $200–1,100
Flights from Columbia to Pensacola International Airport via Charlotte
- Ave. Duration
- 4h 48m
- When
- Every day
- Estimated price
- $140–750
Flights from Columbia to Pensacola International Airport via Reagan Washington
- Ave. Duration
- 5h 52m
- When
- Every day
- Estimated price
- $230–1,100
Flights from Columbia to Pensacola International Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 35m
- When
- Every day
- Estimated price
- $280–1,200
Flights from Columbia to Pensacola International Airport via New York La Guardia
- Ave. Duration
- 6h 13m
- When
- Saturday
- Estimated price
- $290–1,300
- Website
- united.com
Flights from Columbia to Mobile Regional Airport via Washington Dulles
- Ave. Duration
- 6h 16m
- When
- Every day
- Estimated price
- $260–1,200
Flights from Columbia to Pensacola International Airport via Chicago O'Hare
- Ave. Duration
- 7h 44m
- When
- Every day
- Estimated price
- $270–1,200
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Columbia Station to Cary
- Ave. Duration
- 4h 2m
- Frequency
- Once daily
- Estimated price
- $60–130
- Website
- https://www.amtrak.com/home.html
Train from Cary to Greensboro
- Ave. Duration
- 1h 21m
- Frequency
- 5 times a day
- Estimated price
- $23–50
- Website
- https://www.amtrak.com/home.html
Train from Greensboro to New Orleans Union Passenger Terminal
- Ave. Duration
- 21h 40m
- Frequency
- Once daily
- Estimated price
- $280–600
- Website
- https://www.amtrak.com/home.html
Train from New Orleans Union Passenger Terminal to Mobile Amtrak Sta
- Ave. Duration
- 2h 43m
- Frequency
- Twice daily
- Estimated price
- $30–90
- Website
- https://www.amtrak.com/home.html
Train from Columbia Station to Jacksonville
- Ave. Duration
- 5h 57m
- Frequency
- Once daily
- Estimated price
- $90–190
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 803-255-7100
- Website
- catchthecometsc.gov
Bus from Assembly & Gervais South to James E Clyburn Intermodal Transportation Center
- Ave. Duration
- 1h 24m
- Frequency
- Once daily
- Estimated price
- $2
- Schedules at
- catchthecometsc.gov
- Website
- example.com
Bus from Sumter to Atlanta
- Ave. Duration
- 5h 40m
- Frequency
- Once daily
- Schedules at
- example.com
- Website
- greyhound.com
Bus from Atlanta Bus Station to Mobile Bus Station
- Ave. Duration
- 5h 45m
- Frequency
- 5 times a day
- Schedules at
- greyhound.com
Bus from Camden to Atlanta Bus Station
- Ave. Duration
- 5h 10m
- Frequency
- Once daily
- Schedules at
- greyhound.com
Bus from Atlanta Bus Station to Mobile Bus Station
- Ave. Duration
- 5h 45m
- Frequency
- 5 times a day
- Schedules at
- greyhound.com
Bus from Camden to Atlanta Bus Station
- Ave. Duration
- 5h 10m
- Frequency
- Once daily
- Schedules at
- greyhound.com
Bus from Jacksonville to Mobile Bus Station
- Ave. Duration
- 11h 20m
- Frequency
- Once daily
- Schedules at
- greyhound.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Atlanta Bus Station to Mobile Bus Station
- Ave. Duration
- 5h 45m
- Frequency
- 5 times a day
- Estimated price
- $50–100
- Website
- https://www.greyhound.com/
Bus from Pensacola Airport to Mobile Bus Station
- Ave. Duration
- 1h 15m
- Frequency
- Once daily
- Estimated price
- $9–19
- Website
- https://www.greyhound.com/
Bus from Camden to Atlanta Bus Station
- Ave. Duration
- 5h 10m
- Frequency
- Twice daily
- Estimated price
- $35–75
- Website
- https://www.greyhound.com/
Bus from Atlanta Bus Station to Mobile Bus Station
- Ave. Duration
- 5h 45m
- Frequency
- 5 times a day
- Estimated price
- $50–100
- Website
- https://www.greyhound.com/
Bus from Camden to Atlanta Bus Station
- Ave. Duration
- 5h 10m
- Frequency
- Twice daily
- Estimated price
- $35–75
- Website
- https://www.greyhound.com/
Bus from Jacksonville to Mobile Bus Station
- Ave. Duration
- 11h 20m
- Frequency
- Once daily
- Estimated price
- $65–130
- Website
- https://www.greyhound.com/
- Phone
- +1 800-923-1799
- [email protected]
- Website
- omnibusexpress.com
Bus from Gulfport to Mobile
- Ave. Duration
- 1h 13m
- Frequency
- Once daily
- Estimated price
- $45–60
- Schedules at
- omnibusexpress.com
Bus from Atlanta to Grand Bay
- Ave. Duration
- 5h 9m
- Frequency
- Once daily
- Estimated price
- $75–100
- Schedules at
- omnibusexpress.com
Bus from Grand Bay to Mobile
- Ave. Duration
- 24 min
- Frequency
- Once daily
- Estimated price
- $35–50
- Schedules at
- omnibusexpress.com
- Phone
- +1 646-630-7186
- [email protected]
- Website
- wandacoach.com
Bus from Columbia, SC to Camden
- Ave. Duration
- 43 min
- Frequency
- Once daily
- Estimated price
- $28–40
- Website
- https://www.wandacoach.com
- Book at
- https://www.gotobus.com/wanda-travel/
- Adult One Way
- $28–40
Bus from Columbia, SC to Camden
- Ave. Duration
- 43 min
- Frequency
- Once daily
- Estimated price
- $28–40
- Website
- https://www.wandacoach.com
- Book at
- https://www.gotobus.com/wanda-travel/
- Adult One Way
- $28–40
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More Questions & Answers
Columbia to Mobile bus services, operated by The COMET, arrive at James E Clyburn Intermodal Transportation Center station.
Mobile is 1h behind Columbia. It is currently 6:43 PM in Columbia and 5:43 PM in Mobile.
Columbia to Mobile train services, operated by Amtrak, arrive at Cary station.
Yes, the driving distance between Columbia to Mobile is 536 miles. It takes approximately 8h 44m to drive from Columbia to Mobile.
Book your Columbia to Mobile train tickets online with Omio.
There are 190+ hotels available in Mobile.









