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How to get fromColumbia to Mobileby plane, bus (Greyhound), train (Amtrak), car, bus, or train

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There are 7 ways to get from Columbia to Mobile by plane, bus (Greyhound), train (Amtrak), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Mobile Regional Airport

    best
    1. Fly from Columbia (CAE) to Mobile Regional Airport (MOB)plane plane CAE - MOB
    5h 16m
    $92–402

  2. Bus

    1. Take the bus from Columbia, SC to Camdenbus bus
    2. Take the bus from Camden to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Mobile Bus Stationbus bus
    16h 14m
    $114–192

  3. Train (Amtrak)

    1. Take the train from Columbia Station to Carytrain train
    2. Take the train from Cary to Greensborotrain train
    3. Take the train from Greensboro to New Orleans Union Passenger Terminaltrain train
    4. Take the train from New Orleans Union Passenger Terminal to Mobile Amtrak Statrain train
    32h 46m
    $305–789

  4. Drive  533.2 mi

    1. Drive from Columbia to Mobilecar car 533.2 mi
    8h 44m
    $98–141

  5. Fly to Gulfport-Biloxi Regional Airport, bus

    1. Fly from Columbia (CAE) to Gulfport-Biloxi Regional Airport (GPT)plane plane CAE - GPT
    2. Take the bus from Gulfport to Mobilebus bus
    7h 27m
    $134–502

  6. Bus via Grand Bay

    1. Take the bus from Columbia, SC to Camdenbus bus
    2. Take the bus from Camden to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta to Grand Baybus bus
    4. Take the bus from Grand Bay to Mobilebus bus
    16h 36m
    $178–260

  7. Train, bus

    1. Take the train from Columbia Station to Jacksonvilletrain train Floridian
    2. Take the bus from Jacksonville to Mobile Bus Stationbus bus Greyhound US0760S
    20h 30m
    $136–279

Columbia to Mobile by train (Amtrak)

Calendar7Weekly Trains
Duration32h 46mAverage Duration
Ticket$305Cheapest Price
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Comparing Your Travel Options

Map of how to get from Columbia to Mobile.ExpandLaunch map view
  • Distance: 494.9 mi
  • Duration: 5h 16m

What companies run services between Columbia, SC, USA and Mobile, AL, USA?

Delta, American Airlines, and United Airlines fly from Columbia (CAE) to Mobile Regional Airport (MOB) every 3 hours. Alternatively, you can take a bus from Sumter Laurel South to Govt EB Mid Block Past Joachim St via Broad Marley North, Columbia, SC, Camden, Atlanta Bus Station, Mobile Bus Station, and Govt EB at Greyhound Bus Station in around 16h 14m.

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