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How to get fromColumbia to Port Saint Lucieby train, bus, bus (Greyhound), car, plane, or taxi

Find Transport to Port Saint Lucie

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There are 6 ways to get from Columbia to Port Saint Lucie by train, bus, bus (Greyhound), car, plane, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus

    best
    1. Take the train from Columbia Station to Kissimmee Amtrak Stationtrain train Floridian
    2. Take the bus from Kissimmee -1471 East Osceola Parkway to Fort Piercebus bus Orlando to Miami
    13h 38m
    $173–337

  2. Bus

    cheapest
    1. Take the bus from Assembly & Gervais South to James E Clyburn Intermodal Transportation Centerbus bus 44
    2. Take the bus from Sumter Bus Stop to Jacksonvillebus bus
    3. Take the bus from Jacksonville to Port St Luciebus bus
    17h 33m
    $82–162

  3. Drive 521.8 mi

    1. Drive from Columbia to Port Saint Luciecar car 521.8 mi
    8h 36m
    $96–138

  4. Fly Columbia to Melbourne International Airport, taxi, bus

    1. Fly from Columbia (CAE) to Melbourne International Airport (MLB)plane plane CAE - MLB
    2. Take the taxi from Melbourne International Airport (MLB) to Sebastiantaxi taxi
    3. Take the bus from Sebastian to Port St Luciebus bus
    9h 12m
    $242–974

  5. Fly Columbia to President Donald J. Trump International Airport, bus

    1. Fly from Columbia (CAE) to President Donald J. Trump International Airport (PBI)plane plane CAE - PBI
    2. Take the bus from WPB ITC at BAY D to GATLIN BLVD at I-95 P/R LOTbus bus
    9h 45m
    $200–1,018

  6. Bus, bus to Charlotte Douglas International Airport, fly to Vero Beach Municipal Airport, taxi

    1. Take the bus from Columbia, SC to Camdenbus bus
    2. Take the bus from Camden to Charlotte Bus Stationbus bus
    3. Fly from Charlotte Douglas International Airport (CLT) to Vero Beach Municipal Airport (VRB)plane plane CLT - VRB
    4. Take the taxi from Vero Beach Municipal Airport (VRB) to Port Saint Lucietaxi taxi
    9h 22m
    $234–730

Columbia to Port Saint Lucie by train and bus

Calendar7Weekly Services
Duration13h 38mAverage Duration
Ticket$173Cheapest Price
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Questions & Answers

Map of how to get from Columbia to Port Saint Lucie.ExpandLaunch map view
  • Distance: 559.5 mi
  • Duration: 13h 38m

What companies run services between Columbia, SC, USA and Port Saint Lucie, FL, USA?

You can take a bus from Assembly & Gervais South to SW PSL Blvd & SE Bayshore Blvd via James E Clyburn Intermodal Transportation Center, Sumter Bus Stop, Jacksonville, and SW Gatlin Blvd & SW Brescia St in around 17h 33m.

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