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How to get fromColumbia to Sanibelby plane, train, bus, bus (Greyhound, Flixbus), or car

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There are 4 ways to get from Columbia to Sanibel by plane, train, bus, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Columbia (CAE) to Ft. Myers (RSW)plane plane CAE - RSW
    6h 2m
    $266–1,096

  2. Drive 598.6 mi

    cheapest
    1. Drive from Columbia to Sanibelcar car 598.6 mi
    10h 40m
    $110–158

  3. Train, bus

    1. Take the train from Columbia Station to Tampatrain train Floridian
    2. Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus bus FlixBus 2421
    16h 46m
    $252–458

  4. Bus

    1. Take the bus from Assembly & Gervais South to James E Clyburn Intermodal Transportation Centerbus bus 44
    2. Take the bus from Sumter Bus Stop to Jacksonvillebus bus
    3. Take the bus from Jacksonville to Orlando Bus Stationbus bus
    4. Take the bus from Orlando Bus Station to Fort Myers Bus Stopbus bus
    20h 30m
    $144–254

Columbia (CAE) to Ft. Myers (RSW) flights

Calendar91Weekly Planes
Duration5h 41mAverage Duration
Ticket$189Cheapest Price
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Questions & Answers

Map of how to get from Columbia to Sanibel.ExpandLaunch map view
  • Distance: 547.4 mi
  • Duration: 6h 2m

What companies run services between Columbia, SC, USA and Sanibel, FL, USA?

American Airlines, Delta, and United Airlines fly from Columbia (CAE) to Ft. Myers (RSW) hourly. Alternatively, you can take a bus from Assembly & Gervais South to Sanibel via James E Clyburn Intermodal Transportation Center, Sumter Bus Stop, Jacksonville, Orlando Bus Station, Rosa Parks Transportation Ctr, and Cape Coral Transfer Center in around 20h 30m.

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