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How to get fromColumbia to Sanibel Islandby plane, train, bus, bus (Greyhound, Flixbus), or car

Find Transport to Sanibel Island

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There are 5 ways to get from Columbia to Sanibel Island by plane, train, bus, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Columbia (CAE) to Ft. Myers (RSW)plane plane CAE - RSW
    6h
    $156–532

  2. Drive 597.5 mi

    cheapest
    1. Drive from Columbia to Sanibel Islandcar car 597.5 mi
    10h 38m
    $109–158

  3. Train, bus

    1. Take the train from Columbia Station to Tampatrain train Floridian
    2. Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus bus FlixBus 2421
    16h 44m
    $242–451

  4. Bus

    1. Take the bus from Assembly & Gervais South to James E Clyburn Intermodal Transportation Centerbus bus 44
    2. Take the bus from Sumter Bus Stop to Jacksonvillebus bus
    3. Take the bus from Jacksonville to Orlando Bus Stationbus bus
    4. Take the bus from Orlando Bus Station to Fort Myers Bus Stopbus bus
    20h 27m
    $144–244

  5. Train, bus via Tice (Amtrak)

    1. Take the train from Columbia Station to Tampatrain train Floridian
    2. Take the bus from Tampa to Fort Myers Amtrak Bus Stopbus bus Amtrak Thruway Connecting Service
    17h 2m
    $278–497

Columbia (CAE) to Ft. Myers (RSW) flights

Calendar91Weekly Planes
Duration5h 41mAverage Duration
Ticket$82Cheapest Price
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Questions & Answers

Map of how to get from Columbia to Sanibel Island.ExpandLaunch map view
  • Distance: 546.4 mi
  • Duration: 6h

What companies run services between Columbia, SC, USA and Sanibel Island, FL, USA?

American Airlines, Delta, and United Airlines fly from Columbia (CAE) to Ft. Myers (RSW) hourly. Alternatively, you can take a bus from Assembly & Gervais South to Sanibel Island via James E Clyburn Intermodal Transportation Center, Sumter Bus Stop, Jacksonville, Orlando Bus Station, Rosa Parks Transportation Ctr, and Cape Coral Transfer Center in around 20h 27m.

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