There are 6 ways to get from Columbus Airport (CMH) to Knoxville by plane, bus, rideshare, car, bus (Greyhound), or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from John Glenn Columbus International Airport (CMH) to Mcghee Tyson Airport (TYS)plane CMH - TYS
3h 49m$210–961Drive 365.7 mi
cheapest- Drive from Columbus-Airport-CMH to Knoxvillecar 365.7 mi
6h 8m$67–97Bus
- Take the bus from Columbus, OH to New York, NYbus Cincinnati
- Take the bus from New York, NY to Knoxville, TNbus Ny
24h 1m$246–300Airport Transfer
- Take the rideshare from Columbus-CMH to Knoxville365.7 mi
6h 8mBus via Farragut
- Take the bus from Columbus to Port Authority Bus Terminalbus Greyhound US0421
- Take the bus from New York to Knoxvillebus Nyc
30h 39m$275–436Bus via Charlie Haun WB Aft Washington PK
- Take the bus from Columbus to New York City Chinatownbus FlixBus N2640
- Take the bus from New York, NY to Knoxville, TNbus Ny
32h 8m$196–278
John Glenn Columbus International Airport (CMH) to Mcghee Tyson Airport (TYS) flights
Questions & Answers
The cheapest way to get from Columbus Airport (CMH) to Knoxville is to drive which costs $65 - $100 and takes 6h 8m.
The fastest way to get from Columbus Airport (CMH) to Knoxville is to fly which takes 3h 49m and costs $210 - $1,000.
No, there is no direct bus from Columbus Airport (CMH) to Knoxville. However, there are services departing from John Glenn Columbus Intnl Airport and arriving at Knoxville, TN via Columbus, OH and New York, NY. The journey, including transfers, takes approximately 24h 1m.
The distance between Columbus Airport (CMH) and Knoxville is 310 miles. The road distance is 367.8 miles.
The best way to get from Columbus Airport (CMH) to Knoxville without a car is to bus which takes 24h 1m and costs $240 - $300.
It takes approximately 3h 49m to get from Columbus Airport (CMH) to Knoxville, including transfers.
Columbus Airport (CMH) to Knoxville bus services, operated by SkyHorse / Jaguar, depart from Columbus, OH station.
The best way to get from Columbus Airport (CMH) to Knoxville is to fly which takes 3h 49m and costs $210 - $1,000. Alternatively, you can bus, which costs $240 - $300 and takes 24h 1m.
Columbus Airport (CMH) to Knoxville bus services, operated by SkyHorse / Jaguar, arrive at New York, NY station.
Yes, the driving distance between Columbus Airport (CMH) to Knoxville is 368 miles. It takes approximately 6h 8m to drive from Columbus Airport (CMH) to Knoxville.
What companies run services between Columbus Airport (CMH), USA and Knoxville, TN, USA?
Delta, American Airlines, and two other airlines fly from John Glenn Columbus International Airport (CMH) to Mcghee Tyson Airport (TYS) hourly. Alternatively, you can take a bus from John Glenn Columbus Intnl Airport to Knoxville via Columbus - 306 E Mount St, Columbus, OH, New York, NY, and Knoxville, TN in around 24h 1m.
- Website
- delta.com
Flights from John Glenn Columbus International Airport to Mcghee Tyson Airport via Atlanta
- Ave. Duration
- 4h 22m
- When
- Every day
- Estimated price
- $170–950
Flights from John Glenn Columbus International Airport to Mcghee Tyson Airport via Detroit
- Ave. Duration
- 4h 48m
- When
- Every day
- Estimated price
- $170–950
- Website
- aa.com
Flights from John Glenn Columbus International Airport to Mcghee Tyson Airport via Charlotte
- Ave. Duration
- 4h
- When
- Monday to Saturday
- Estimated price
- $160–950
Flights from John Glenn Columbus International Airport to Mcghee Tyson Airport via Reagan Washington
- Ave. Duration
- 4h 43m
- When
- Sunday
- Estimated price
- $200–1,100
- Website
- southwest.com
Flights from John Glenn Columbus International Airport to Mcghee Tyson Airport via Baltimore
- Ave. Duration
- 4h 25m
- When
- Saturday, Monday, Thursday, Friday, and Sunday
- Estimated price
- $200–1,100
Flights from John Glenn Columbus International Airport to Mcghee Tyson Airport via Nashville
- Ave. Duration
- 4h 52m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $150–900
- Website
- united.com
Flights from John Glenn Columbus International Airport to Mcghee Tyson Airport via Washington Dulles
- Ave. Duration
- 4h 28m
- When
- Every day
- Estimated price
- $190–1,100
- Phone
- +1 917.398.0398
- Website
- skyhorsebus.com
Bus from Columbus, OH to New York, NY
- Ave. Duration
- 9h 30m
- Frequency
- Once daily
- Estimated price
- $110
- Schedules at
- GotoBus.com - NY-OH Ticket Inc
- Phone
- +1 615-939-8887
- [email protected]
- Website
- New York to Tennessee Bus
Bus from New York, NY to Knoxville, TN
- Ave. Duration
- 12h
- Frequency
- Once daily
- Estimated price
- $95–110
- Website
- New York to Tennessee Bus
- Adult One-way
- $95–110
Bus from New York, NY to Knoxville, TN
- Ave. Duration
- 12h
- Frequency
- Once daily
- Estimated price
- $95–110
- Website
- New York to Tennessee Bus
- Adult One-way
- $95–110
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Columbus to Port Authority Bus Terminal
- Ave. Duration
- 15h 5m
- Frequency
- 3 times a day
- Estimated price
- $90–180
- Website
- Greyhound
- Phone
- +1 646-630-7186
- [email protected]
- Website
- Wanda Coach
Bus from New York to Knoxville
- Ave. Duration
- 11h 45m
- Frequency
- Once daily
- Estimated price
- $95–140
- Website
- Wanda Coach
- Book at
- GotoBus.com
- Adult One Way
- $95–140
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Columbus to New York City Chinatown
- Ave. Duration
- 13h 15m
- Frequency
- 6 times a week
- Estimated price
- $95–160
- Schedules at
- Flixbus USA
- Website
- https://www.mozio.com
Rideshare from Columbus-CMH to Knoxville
- Ave. Duration
- 6h 8m
- Frequency
- On demand
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
More Questions & Answers
There are 271+ hotels available in Knoxville.
Check out Blablacar's carpooling service for rideshare options between Columbus Airport (CMH) and Knoxville. A great option if you don't have a driver's licence or want to avoid public transport.



